UVM  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples80
No. mutated genes6701
No. SNVs1572
No. CNAs180

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
GNAQ404010>>>>
GNA11363600>>>>
BAP12626180>>>>
SF3B1181800>>>>
C11orf58170017>>>>
EXT1160016>>>>
NDRG1160016>>>>
CYC1161016>>>>
MYC160016>>>>
LINC00536160016>>>>
PARP10160016>>>>
EIF1AX101000>>>>
NEDD99009>>>>
DEK9009>>>>
MUC165500>>>>
TTN5500>>>>
PCSK74103>>>>
SLC22A144103>>>>
MDS24004>>>>
FLI14004>>>>
ARHGEF123003>>>>
PKHD1L13300>>>>
CBL3003>>>>
MYOF3310>>>>
DDX63003>>>>
PAFAH1B23003>>>>
CYSLTR23300>>>>
CSMD33300>>>>
PLCB23310>>>>
RYR23300>>>>
SRSF23300>>>>
COL14A13300>>>>
ARHGEF172200>>>>
MUC42200>>>>
TPCN12210>>>>
USP342200>>>>
UTRN2200>>>>
EVC2200>>>>
PANK42210>>>>
ING52002>>>>
PPP1R3A2200>>>>
SETX2200>>>>
RPTN2200>>>>
SELE2200>>>>
EIF1B2210>>>>
E2F72210>>>>
MAP3K192200>>>>
SYTL32200>>>>
HUWE12200>>>>
PPL2200>>>>
CDH42210>>>>
CENPE2200>>>>
APC2200>>>>
HSD17B72200>>>>
ELMO22200>>>>
ADAMTSL12200>>>>
TNS32200>>>>
SPEG2200>>>>
MAOB2210>>>>
MYBPC22200>>>>
DEPDC52200>>>>
LUZP12200>>>>
HDAC52200>>>>
WDR162200>>>>
AZI12200>>>>
HSPG22210>>>>
WISP12200>>>>
TMEM22200>>>>
OBSCN2200>>>>
ETS12210>>>>
HDLBP2200>>>>
GNB12200>>>>
USP492210>>>>
SCN8A2210>>>>
NRK2220>>>>
PCDHB72200>>>>
CACNA1B2200>>>>
CACNA1D2200>>>>
PLCB42200>>>>
MYO1F2210>>>>
RRNAD12210>>>>
C32200>>>>
KCNH52200>>>>
GMEB22210>>>>
TYRP12220>>>>
IYD2200>>>>
KMT2D2200>>>>
SEL1L32200>>>>
PPP6R22210>>>>
REC82200>>>>
SPTA12200>>>>
DNAH172200>>>>
TBX62200>>>>
MC2R2200>>>>
RNF432200>>>>
CACNA2D12200>>>>
FAT12200>>>>
MYO15A2200>>>>
SLC19A12200>>>>
GLIS32200>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Calcium signaling pathway - Homo sapiens (human)177KEGG7911260View
Long-term depression - Homo sapiens (human)72KEGG769130View
Vascular smooth muscle contraction - Homo sapiens (human)115KEGG759233View
Gap junction - Homo sapiens (human)90KEGG759040View
GnRH signaling pathway - Homo sapiens (human)101KEGG759140View
Alzheimer's disease - Homo sapiens (human)166KEGG5657416View
Huntington's disease - Homo sapiens (human)179KEGG5254616View
Long-term potentiation - Homo sapiens (human)70KEGG485430View
Melanogenesis - Homo sapiens (human)101KEGG455240View
MAPK signaling pathway - Homo sapiens (human)269KEGG3332616View
Pathways in cancer - Homo sapiens (human)329KEGG3332619View
Wnt signaling pathway - Homo sapiens (human)150KEGG2918216View
Jak-STAT signaling pathway - Homo sapiens (human)155KEGG259219View
Cardiac muscle contraction - Homo sapiens (human)76KEGG2413016View
B-WICH; ISWI8PINdb241809View
ErbB signaling pathway - Homo sapiens (human)87KEGG236119View
TGF-beta signaling pathway - Homo sapiens (human)86KEGG228016View
Cell cycle - Homo sapiens (human)125KEGG217216View
Colorectal cancer - Homo sapiens (human)84KEGG218016View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG213019View