UCS  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples57
No. mutated genes9525
No. SNVs7650
No. CNAs693

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP535151130>>>>
FSTL3290029>>>>
TCF3280028>>>>
GNA11280028>>>>
MAP2K2270027>>>>
STK11270027>>>>
ZNF536272026>>>>
SH3GL1251025>>>>
FBXW7222220>>>>
PDE4D212019>>>>
PIK3CA202000>>>>
EGFEM1P190019>>>>
BCL2L1191018>>>>
LRP1B185215>>>>
FGFR3170017>>>>
LETM1170017>>>>
MYC172015>>>>
PPP2R1A161600>>>>
BUB1B160016>>>>
FHIT140014>>>>
HOOK3141014>>>>
SOX17141113>>>>
RB113649>>>>
PBRM1122110>>>>
NEDD9120012>>>>
TCEA1110011>>>>
PLAG1111011>>>>
WWOX111011>>>>
CHCHD7110011>>>>
PTEN111160>>>>
CAMTA1100010>>>>
CHD4101030>>>>
PRDM16100010>>>>
RPL22100010>>>>
TTN9900>>>>
CSMD19009>>>>
SDHB8008>>>>
PAX78008>>>>
GAS77007>>>>
KRAS7700>>>>
MUC177700>>>>
PTPRD7117>>>>
ARID1A7740>>>>
LINC002907007>>>>
MAP2K47116>>>>
VDAC27007>>>>
PPP2R2A6006>>>>
MUC166610>>>>
ARHGAP356650>>>>
AHNAK6600>>>>
ZBTB7B6620>>>>
VPS13B6620>>>>
MGAM6610>>>>
FLNA6600>>>>
KAT6B6006>>>>
SYNE16610>>>>
KMT2D6610>>>>
PIK3R16630>>>>
NRXN15510>>>>
FER1L65520>>>>
PCM15005>>>>
FCGBP5500>>>>
DOPEY15510>>>>
ATP4A5500>>>>
LRP25510>>>>
GPRASP14410>>>>
PRPF84400>>>>
FAM135B4410>>>>
CACNA1A4410>>>>
MAP3K44420>>>>
EPG54410>>>>
KIAA12174410>>>>
KLHL44400>>>>
MED124410>>>>
MKI674400>>>>
FBN34400>>>>
USH2A4400>>>>
ADAMTSL14430>>>>
CREBBP4410>>>>
EBF24410>>>>
ERBB34400>>>>
ABCA124400>>>>
MAGEC24400>>>>
NF14410>>>>
SPOP4400>>>>
SYCP24400>>>>
BRWD14400>>>>
PCLO4400>>>>
SI4400>>>>
PDGFRB4400>>>>
DPP104410>>>>
REV3L4410>>>>
ASTN14400>>>>
DNAH24410>>>>
DNAH94400>>>>
GRIA34410>>>>
INADL4410>>>>
PLEC4410>>>>
EPHA54400>>>>
FMN24400>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
MAPK signaling pathway - Homo sapiens (human)269KEGG571803565View
Apoptosis - Homo sapiens (human)87KEGG571052018View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG571182127View
Pathways in cancer - Homo sapiens (human)329KEGG572474586View
Pancreatic cancer - Homo sapiens (human)72KEGG571192427View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG571152369View
Small cell lung cancer - Homo sapiens (human)86KEGG571363256View
Wnt signaling pathway - Homo sapiens (human)150KEGG561372528View
Huntington's disease - Homo sapiens (human)179KEGG561052315View
Colorectal cancer - Homo sapiens (human)84KEGG561192015View
Glioma - Homo sapiens (human)65KEGG561202736View
Prostate cancer - Homo sapiens (human)89KEGG561283036View
Melanoma - Homo sapiens (human)71KEGG561232836View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG551261744View
Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human)55KEGG55691418View
Endometrial cancer - Homo sapiens (human)52KEGG551102542View
Bladder cancer - Homo sapiens (human)42KEGG55791868View
Non-small cell lung cancer - Homo sapiens (human)54KEGG551052150View
Cell cycle - Homo sapiens (human)125KEGG541092940View
p53 signaling pathway - Homo sapiens (human)68KEGG5487230View