UCEC  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples248
No. mutated genes17692
No. SNVs130691
No. CNAs1281

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
PTEN17216111516>>>>
PIK3CA13113100>>>>
ARID1A103837622>>>>
PIK3R18080410>>>>
TTN797900>>>>
CTNNB1747400>>>>
TP536969140>>>>
KRAS5852010>>>>
LRP1B49291020>>>>
CSMD34747100>>>>
MUC164646130>>>>
MAP2K2454042>>>>
GNA11442042>>>>
ZFHX34444210>>>>
CTCF4444290>>>>
FAT14040180>>>>
FAT44040140>>>>
MUC5B404060>>>>
RYR24040110>>>>
NOTCH33916023>>>>
OBSCN383850>>>>
DMD3838100>>>>
FBXW7383890>>>>
TERC380038>>>>
EGFEM1P370037>>>>
ZFHX4363680>>>>
ARHGAP353636240>>>>
CHD4353520>>>>
NEB3535130>>>>
TAF1353540>>>>
FAT3353590>>>>
USH2A3535110>>>>
DNAH53535100>>>>
ARNT345329>>>>
RYR3343480>>>>
KMT2D333380>>>>
ERBB33317016>>>>
NF13320813>>>>
MDN1333370>>>>
LRP2333360>>>>
SYNE13333100>>>>
ERBB2328024>>>>
ABCA13323260>>>>
FLG323250>>>>
DNAH10323260>>>>
BRD4318023>>>>
NBEA313160>>>>
HERC1313170>>>>
PCLO3131110>>>>
ANK3313190>>>>
RYR1313130>>>>
MCL1301029>>>>
APOB303050>>>>
CSMD2303030>>>>
LAMA23030100>>>>
FGFR2303040>>>>
KMT2B3030100>>>>
CACNA1E303070>>>>
UBR4303030>>>>
BCOR303030>>>>
KAT6A3015116>>>>
MUC17303020>>>>
DNAH113030140>>>>
APC2929140>>>>
AKAP8295224>>>>
ATM2929150>>>>
HMCN12929130>>>>
MKI672929160>>>>
PCDH152929100>>>>
GPR112292920>>>>
DNAH9292970>>>>
DNAH2292990>>>>
ARID5B2929140>>>>
TENM1292940>>>>
CREBBP282246>>>>
AKAP92828130>>>>
SPTA1282850>>>>
MACF12828100>>>>
DST282870>>>>
ASPM2828130>>>>
AHNAK2282850>>>>
DNM2285123>>>>
GPR98272780>>>>
BIRC6272760>>>>
CSMD1272770>>>>
PPP2R1A272710>>>>
HERC22727100>>>>
SMG1272770>>>>
DNAH72727110>>>>
POLE272710>>>>
HUWE1272750>>>>
LRP1272720>>>>
DSCAM272730>>>>
UTRN262660>>>>
CHD3262650>>>>
AHNAK262640>>>>
MGA2626140>>>>
PTPRD262135>>>>
WHSC12612214>>>>
CCNE1265121>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG2472801536245View
Endometrial cancer - Homo sapiens (human)52KEGG247916236126View
Prostate cancer - Homo sapiens (human)89KEGG2471166270139View
Glioma - Homo sapiens (human)65KEGG24490323188View
Focal adhesion - Homo sapiens (human)199KEGG243207742854View
Small cell lung cancer - Homo sapiens (human)86KEGG243116130090View
Melanoma - Homo sapiens (human)71KEGG24283922888View
Colorectal cancer - Homo sapiens (human)84KEGG23994514435View
Insulin signaling pathway - Homo sapiens (human)137KEGG236112016972View
ErbB signaling pathway - Homo sapiens (human)87KEGG235824122138View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG235166727381View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG234102116372View
Renal cell carcinoma - Homo sapiens (human)70KEGG234657105101View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG234779117114View
Jak-STAT signaling pathway - Homo sapiens (human)155KEGG232101115242View
Acute myeloid leukemia - Homo sapiens (human)57KEGG2326349786View
Non-small cell lung cancer - Homo sapiens (human)54KEGG232660103107View
Apoptosis - Homo sapiens (human)87KEGG23172614616View
Fc epsilon RI signaling pathway - Homo sapiens (human)79KEGG2316639372View
Pancreatic cancer - Homo sapiens (human)72KEGG23177613661View