THYM  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples120
No. mutated genes6906
No. SNVs1864
No. CNAs90

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
GTF2I494910>>>>
HRAS101000>>>>
CDKN2A9118>>>>
TTN8800>>>>
CHEK28216>>>>
EWSR17007>>>>
NF27116>>>>
ZNRF37007>>>>
MUC166610>>>>
MN15005>>>>
UNC93B15500>>>>
SERPINB65005>>>>
PBRM14212>>>>
SETD24103>>>>
TP534410>>>>
SRGAP34004>>>>
CNTN44004>>>>
MITF4004>>>>
FOXP13003>>>>
DMD3300>>>>
PCLO3300>>>>
ZNF2083300>>>>
ROBO13112>>>>
BCOR3320>>>>
NRAS3300>>>>
NF13310>>>>
MYH143300>>>>
DNAH33310>>>>
CAPNS13300>>>>
CTNNB13102>>>>
PLEKHG4B3320>>>>
L3MBTL33310>>>>
ATRN3300>>>>
FHIT2002>>>>
NR0B12200>>>>
IRX32210>>>>
XPC2002>>>>
GTF3C12200>>>>
COL4A12200>>>>
NRXN12200>>>>
CSMD22200>>>>
MRGPRX32210>>>>
SMARCA42200>>>>
BRD42200>>>>
UTRN2210>>>>
DNAJC272200>>>>
PAX72200>>>>
EPG52210>>>>
SF3B12200>>>>
COL6A52200>>>>
COL6A62200>>>>
FAT42210>>>>
CHD32210>>>>
MLH32200>>>>
MLH12111>>>>
SIN3A2200>>>>
OTOGL2200>>>>
KAT6A2200>>>>
USP9X2210>>>>
ATP1A22210>>>>
PPARG2002>>>>
MECP22200>>>>
NLGN4X2200>>>>
SCN1A2200>>>>
CLIP22200>>>>
TENM42210>>>>
PVR2200>>>>
RNF1462200>>>>
PPP4R42200>>>>
SYNE22210>>>>
SPEN2210>>>>
KRTAP4-82210>>>>
NT5C1B2200>>>>
MUC212200>>>>
MYD882002>>>>
GET42200>>>>
FOXN12200>>>>
SETMAR2210>>>>
JPH32200>>>>
TMEM63B2210>>>>
MORC22200>>>>
WDR812200>>>>
LGALS3BP2200>>>>
DMXL12210>>>>
RP1L12200>>>>
REV3L2200>>>>
CYLD2210>>>>
DHX332200>>>>
PHEX2210>>>>
DNAH12210>>>>
DNAH52200>>>>
AGAP12200>>>>
PHF102210>>>>
NOD12210>>>>
C1orf1272210>>>>
AXL2200>>>>
BRCA22200>>>>
ZAN2210>>>>
DOCK22200>>>>
CTNND22210>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
HDAC2; HDAC2-containing; HDAC2/BHC110-containing; BHC110/HDAC2-containing17PINdb535430View
Basal transcription factors - Homo sapiens (human)35KEGG515210View
XFIM; BHC110-containing; HDAC1,2-containing; F-XFIM; XFIM-associated4PINdb505020View
BHC110; BHC110-containing; HDAC2/BHC110-containing; BHC110/HDAC2-containing13PINdb505020View
DYX1C1 transcription; DYX1C1 promoter3PINdb505010View
Pathways in cancer - Homo sapiens (human)329KEGG4560821View
MAPK signaling pathway - Homo sapiens (human)269KEGG354882View
Melanoma - Homo sapiens (human)71KEGG3226514View
Glioma - Homo sapiens (human)65KEGG3127410View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG3128410View
Non-small cell lung cancer - Homo sapiens (human)54KEGG3126412View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG293342View
Focal adhesion - Homo sapiens (human)199KEGG283754View
Insulin signaling pathway - Homo sapiens (human)137KEGG283642View
Bladder cancer - Homo sapiens (human)42KEGG2723210View
Chemokine signaling pathway - Homo sapiens (human)190KEGG262922View
Endometrial cancer - Homo sapiens (human)52KEGG252645View
Melanogenesis - Homo sapiens (human)101KEGG242618View
Prostate cancer - Homo sapiens (human)89KEGG242634View
Acute myeloid leukemia - Homo sapiens (human)57KEGG242332View