TGCT  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples147
No. mutated genes9625
No. SNVs7916
No. CNAs782

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
KRAS4119025>>>>
KIT3926015>>>>
ZNF384282126>>>>
KDM5A272025>>>>
TVP23C-CDRT4262600>>>>
CCND2250025>>>>
PKP2210021>>>>
WWOX170017>>>>
CBFA2T3171016>>>>
PIK3CA163014>>>>
FANCA161116>>>>
FLI1160016>>>>
PDGFRA161015>>>>
MUC2161600>>>>
MUC6151500>>>>
KDR150015>>>>
DNMT3A141013>>>>
BCL6140014>>>>
EIF4A2140014>>>>
MAF140014>>>>
MYCN141013>>>>
TERC140014>>>>
SOX17140014>>>>
LPP140014>>>>
FIP1L1140014>>>>
ALK142012>>>>
SOX2140014>>>>
ETV5140014>>>>
TCEA1130013>>>>
PRDM16132011>>>>
AKAP9132111>>>>
FBXO11132011>>>>
PARK2130013>>>>
C2orf44130013>>>>
NCOA1130013>>>>
PLAG1120012>>>>
CHCHD7120012>>>>
EML4120012>>>>
MSH2121011>>>>
MSH6121011>>>>
RPL22121111>>>>
CDK6110011>>>>
PMS211209>>>>
TTN111100>>>>
CAMTA1110011>>>>
CLTCL1110011>>>>
CELSR1101000>>>>
LAMA5101000>>>>
ELN10109>>>>
PLEC101010>>>>
SDHB9108>>>>
CARD119108>>>>
OBSCN8820>>>>
HIP18107>>>>
PAX78008>>>>
DDX118830>>>>
NEGR18008>>>>
JAK18117>>>>
ERC17700>>>>
FAM104B7750>>>>
ANKRD117700>>>>
CBFB7007>>>>
NRAS7700>>>>
MUC177700>>>>
MUC167700>>>>
CDH117007>>>>
NBPF107700>>>>
AHNAK27710>>>>
CDH17007>>>>
SP86600>>>>
SBDS6006>>>>
RHPN26600>>>>
STAB16600>>>>
HSF46600>>>>
FAT36610>>>>
HERPUD16105>>>>
KMT2B6630>>>>
SZT26630>>>>
MDS26006>>>>
CDC276640>>>>
LAMC36600>>>>
HUWE16610>>>>
CRB26600>>>>
DSCAML16600>>>>
CREBBP6610>>>>
MEGF86610>>>>
ZNRF36600>>>>
ARID1A6115>>>>
SDK15510>>>>
KRTAP10-105500>>>>
TERF25005>>>>
DEK5500>>>>
CUX15520>>>>
RP11-1055B8-75500>>>>
SPTBN55500>>>>
SPTBN45500>>>>
ZNF8145500>>>>
UNC795500>>>>
NEB5500>>>>
EZR5005>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG13024722121View
Focal adhesion - Homo sapiens (human)199KEGG111150969View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG1111611359View
MAPK signaling pathway - Homo sapiens (human)269KEGG1071541240View
Insulin signaling pathway - Homo sapiens (human)137KEGG1001171139View
Chemokine signaling pathway - Homo sapiens (human)190KEGG95108639View
Calcium signaling pathway - Homo sapiens (human)177KEGG931261015View
Melanogenesis - Homo sapiens (human)101KEGG9397440View
Wnt signaling pathway - Homo sapiens (human)150KEGG9278939View
Endocytosis - Homo sapiens (human)185KEGG91115761View
Acute myeloid leukemia - Homo sapiens (human)57KEGG9181354View
Tight junction - Homo sapiens (human)132KEGG901071125View
Axon guidance - Homo sapiens (human)129KEGG87107525View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG8794839View
Colorectal cancer - Homo sapiens (human)84KEGG8765376View
Prostate cancer - Homo sapiens (human)89KEGG8472659View
Natural killer cell mediated cytotoxicity - Homo sapiens (human)137KEGG8375242View
Melanoma - Homo sapiens (human)71KEGG8251277View
B cell receptor signaling pathway - Homo sapiens (human)75KEGG8169247View
Renal cell carcinoma - Homo sapiens (human)70KEGG8180639View