SKCM  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples290
No. mutated genes17409
No. SNVs154748
No. CNAs2296

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TTN21221200>>>>
MUC16200200240>>>>
BRAF155145135>>>>
DNAH5153153300>>>>
CDKN2A132402598>>>>
PCLO129129160>>>>
LRP1B110110220>>>>
CSMD1107107140>>>>
GPR98105105160>>>>
NRAS10487217>>>>
RP110310360>>>>
PKHD1L1102102110>>>>
DNAH89999170>>>>
MGAM999970>>>>
DNAH79898200>>>>
APOB9797100>>>>
CSMD39696200>>>>
XIRP2969670>>>>
ANK39696140>>>>
DSCAM959550>>>>
FAT3939380>>>>
FLG939370>>>>
CSMD29292100>>>>
THSD7B9191150>>>>
USH2A9191100>>>>
MXRA5909040>>>>
FAT4888870>>>>
DNAH98787120>>>>
MUC17878730>>>>
PTPRT8484120>>>>
DNAH38484150>>>>
PCDH15838390>>>>
PAPPA28080130>>>>
HYDIN777780>>>>
ASXL3767640>>>>
ZFHX4767670>>>>
SPHKAP767670>>>>
SCN11A757590>>>>
RYR17575100>>>>
MROH2B7474110>>>>
RYR27474110>>>>
COL4A4737350>>>>
MYH2737370>>>>
SYNE17373130>>>>
GRIN2A727260>>>>
UNC13C727270>>>>
DNAH11717170>>>>
NEB7070140>>>>
SCN5A707090>>>>
MYH4707080>>>>
PREX2707070>>>>
DMBT16868100>>>>
MYH1686850>>>>
DCC6868140>>>>
SCN10A676780>>>>
SI6767100>>>>
NPAP1676760>>>>
SPTA1666670>>>>
C1orf173666630>>>>
FLG2666660>>>>
ZNF831656520>>>>
CNTN5656540>>>>
MAGEC1656550>>>>
CD163656520>>>>
DNAH10656590>>>>
TPTE6464110>>>>
LRP2646450>>>>
OBSCN636370>>>>
TENM3636390>>>>
RELN6262110>>>>
FAM135B626240>>>>
MYO18B626240>>>>
PLCB4616190>>>>
STAB2616160>>>>
TENM1616140>>>>
PEG3616150>>>>
TRANK1606050>>>>
SVEP1606040>>>>
CACNA1E606060>>>>
DSP606060>>>>
FCGBP606080>>>>
GPR112606010>>>>
CNTNAP2595970>>>>
KCNB2595950>>>>
COL3A15959100>>>>
TNXB595920>>>>
RYR35959110>>>>
MECOM585820>>>>
KIAA15495828031>>>>
PTPRB585890>>>>
STXBP5L585840>>>>
ABCA13575710>>>>
FMN2575720>>>>
ZNF804A575770>>>>
FAM83B575770>>>>
TMEM132B565610>>>>
KIAA2022565680>>>>
ANKRD30A5656100>>>>
PRUNE2565650>>>>
COL5A1565640>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG2873040334480View
MAPK signaling pathway - Homo sapiens (human)269KEGG2832344235122View
Melanoma - Homo sapiens (human)71KEGG282829105329View
Focal adhesion - Homo sapiens (human)199KEGG2813022288143View
Glioma - Homo sapiens (human)65KEGG281830104299View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG279203117677View
Prostate cancer - Homo sapiens (human)89KEGG27993293237View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG27876889256View
Bladder cancer - Homo sapiens (human)42KEGG27757883242View
Non-small cell lung cancer - Homo sapiens (human)54KEGG27768884202View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG274102382131View
Long-term depression - Homo sapiens (human)72KEGG27311269780View
Endometrial cancer - Homo sapiens (human)52KEGG27368671128View
Acute myeloid leukemia - Homo sapiens (human)57KEGG27361631117View
Chemokine signaling pathway - Homo sapiens (human)190KEGG272135110876View
Long-term potentiation - Homo sapiens (human)70KEGG27210698080View
Renal cell carcinoma - Homo sapiens (human)70KEGG27172153127View
Insulin signaling pathway - Homo sapiens (human)137KEGG27012188852View
Thyroid cancer - Homo sapiens (human)29KEGG27044141158View
ErbB signaling pathway - Homo sapiens (human)87KEGG2689206473View