SARC  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples247
No. mutated genes10636
No. SNVs11902
No. CNAs2609

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP53131853375>>>>
RB184242370>>>>
MDM2601059>>>>
ATRX60363024>>>>
ING5580058>>>>
FAT1508344>>>>
MAP2K4502048>>>>
ARNT470047>>>>
MCL1460046>>>>
CDKN2A461146>>>>
LINC00290430043>>>>
FLI1431043>>>>
NF1439534>>>>
ZNF132410041>>>>
CCNE1410041>>>>
TRIM28410041>>>>
PRDM16402139>>>>
ARHGEF12390039>>>>
CBL390039>>>>
H3F3A370037>>>>
SIRT3372135>>>>
POU2AF1370037>>>>
PCSK7360036>>>>
ZMYND11361035>>>>
PAFAH1B2360036>>>>
SDHD360036>>>>
TERT361036>>>>
DDX6350035>>>>
FH340034>>>>
ATM334130>>>>
SMYD3330033>>>>
PTEN317224>>>>
JUN310031>>>>
DDX10311030>>>>
GNAS292027>>>>
TTN272700>>>>
RAD51B260026>>>>
DMD257019>>>>
BPTF252023>>>>
SS18L1250025>>>>
CBX8253022>>>>
BRIP1241024>>>>
CDKN1B240024>>>>
CANT1240024>>>>
PBRM1242122>>>>
SRSF2230023>>>>
PRKAR1A230023>>>>
MUC16232310>>>>
NOTCH1221121>>>>
BAP1220022>>>>
ETV6220022>>>>
DEK210021>>>>
RFNG210021>>>>
TSC1211020>>>>
SETD2212019>>>>
ASPSCR1200020>>>>
ZNF217200020>>>>
TUBD1201019>>>>
GPHN200020>>>>
BRD3191018>>>>
DDX5191118>>>>
GTF3C4190019>>>>
CLTC182117>>>>
RALGDS180018>>>>
WWOX180018>>>>
CD79B180018>>>>
PRDM13181017>>>>
FHIT180018>>>>
PCLO171720>>>>
CYLD160016>>>>
BIRC3140014>>>>
TSHR140014>>>>
TFEB130013>>>>
USH2A131310>>>>
CCND3130013>>>>
MUC17121210>>>>
DNAH5121230>>>>
GPR98111100>>>>
LRP2111120>>>>
SCN2A111110>>>>
RYR1111130>>>>
AHNAK101010>>>>
CSMD1101010>>>>
FAT3101020>>>>
PKHD1L1101010>>>>
RYR2101010>>>>
HYDIN9920>>>>
APOB9920>>>>
LRP1B9900>>>>
SPHKAP9910>>>>
DNAH89930>>>>
ZNF8318800>>>>
OBSCN8820>>>>
FLG8800>>>>
NUMBL8800>>>>
SCN9A8810>>>>
MUC5B8800>>>>
FREM28800>>>>
DNAH78820>>>>
DNAH98810>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG231393105522View
Cell cycle - Homo sapiens (human)125KEGG22117670358View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG22016263313View
Glioma - Homo sapiens (human)65KEGG21816268274View
Melanoma - Homo sapiens (human)71KEGG21816667274View
Bladder cancer - Homo sapiens (human)42KEGG21414062250View
p53 signaling pathway - Homo sapiens (human)68KEGG21312243288View
Prostate cancer - Homo sapiens (human)89KEGG21217466293View
MAPK signaling pathway - Homo sapiens (human)269KEGG20128759188View
Small cell lung cancer - Homo sapiens (human)86KEGG18721774266View
Pancreatic cancer - Homo sapiens (human)72KEGG18215365209View
Non-small cell lung cancer - Homo sapiens (human)54KEGG17814766209View
Apoptosis - Homo sapiens (human)87KEGG17213142142View
Colorectal cancer - Homo sapiens (human)84KEGG17215443124View
Wnt signaling pathway - Homo sapiens (human)150KEGG17017746119View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG17015739106View
Huntington's disease - Homo sapiens (human)179KEGG16915744128View
Focal adhesion - Homo sapiens (human)199KEGG1572433382View
Endometrial cancer - Homo sapiens (human)52KEGG1541354399View
Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human)55KEGG1421263675View