READ  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples122
No. mutated genes12964
No. SNVs24280
No. CNAs644

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
APC11010810311>>>>
TP539191260>>>>
KRAS636310>>>>
TTN555500>>>>
RBFOX1411040>>>>
PTEN383337>>>>
PIK3CA363610>>>>
PARK2313030>>>>
ARID1A3111721>>>>
SMAD4292546>>>>
FBXW7282880>>>>
ATM242450>>>>
ASXL1246119>>>>
SYNE1242430>>>>
CSMD3222220>>>>
PAX7221021>>>>
CAMTA1224019>>>>
SDHB210021>>>>
TCF7L2211358>>>>
MUC16202020>>>>
MDS2200020>>>>
RYR2202020>>>>
CTNNB1191900>>>>
RPL22190019>>>>
TOP1182016>>>>
FLT3188113>>>>
NF1171750>>>>
BCL2L1170017>>>>
MAFB170017>>>>
ERBB216909>>>>
VHL161610>>>>
KIT161610>>>>
CSMD1161620>>>>
NRAS161105>>>>
FLG161600>>>>
TENM1161620>>>>
DNAH11151510>>>>
OBSCN141440>>>>
LRP1B141430>>>>
FMN2141400>>>>
USH2A141420>>>>
RB1141430>>>>
SMAD313508>>>>
PTCH1131330>>>>
CDX2130013>>>>
HYDIN131320>>>>
APOB131310>>>>
WWOX132011>>>>
TAF1L131310>>>>
FAT4131310>>>>
BRAF131310>>>>
DNAH5131330>>>>
USP12130013>>>>
BRCA2121220>>>>
ZFHX4121230>>>>
FGFR212824>>>>
CDH1121220>>>>
RNF213121220>>>>
RYR1121200>>>>
SPTA1111100>>>>
FAT3111120>>>>
BAI3111100>>>>
UNC13C111120>>>>
CRIPAK111170>>>>
PTPN11101000>>>>
NOTCH210624>>>>
HMCN1101010>>>>
NALCN101000>>>>
FAT110535>>>>
ASH1L101010>>>>
ATP10A101010>>>>
FGFR110208>>>>
AMER1101080>>>>
XIRP2101010>>>>
EP300101040>>>>
TLX110307>>>>
LRP2101000>>>>
COL6A3101010>>>>
LRRK2101020>>>>
MLK4101000>>>>
FREM2101020>>>>
TRIM3310505>>>>
PKHD1101020>>>>
CREBBP101020>>>>
AHNAK2101020>>>>
C5orf429910>>>>
ABCA129920>>>>
LRRC79920>>>>
TMX39207>>>>
MXRA59920>>>>
DPYD9910>>>>
NFKB29207>>>>
DST9910>>>>
HPSE29306>>>>
MUC179900>>>>
EGFR9900>>>>
ANK29930>>>>
LETM29108>>>>
PRDM98800>>>>
DMD8820>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG122989240128View
Wnt signaling pathway - Homo sapiens (human)150KEGG12144916740View
MAPK signaling pathway - Homo sapiens (human)269KEGG1205257130View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG12053015828View
Colorectal cancer - Homo sapiens (human)84KEGG12051116333View
Endometrial cancer - Homo sapiens (human)52KEGG12047314940View
Pancreatic cancer - Homo sapiens (human)72KEGG1193605440View
Basal cell carcinoma - Homo sapiens (human)55KEGG11930614626View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG1193494836View
Prostate cancer - Homo sapiens (human)89KEGG1184336541View
Thyroid cancer - Homo sapiens (human)29KEGG1182403824View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG1173594611View
Bladder cancer - Homo sapiens (human)42KEGG1162633714View
Melanoma - Homo sapiens (human)71KEGG1153534820View
Glioma - Homo sapiens (human)65KEGG1143444512View
Non-small cell lung cancer - Homo sapiens (human)54KEGG1143063814View
Cell cycle - Homo sapiens (human)125KEGG1122915921View
Small cell lung cancer - Homo sapiens (human)86KEGG1122835524View
Apoptosis - Homo sapiens (human)87KEGG1102324423View
Huntington's disease - Homo sapiens (human)179KEGG1092264926View