PRAD  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples498
No. mutated genes13349
No. SNVs24137
No. CNAs2276

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TMPRSS214552142>>>>
ZNF29214363138>>>>
LCP114110140>>>>
PTEN1261711121>>>>
TP53121571787>>>>
ERG10600106>>>>
CHD1828576>>>>
IL6ST756373>>>>
CDKN1B736669>>>>
PIK3R1731072>>>>
TTN626200>>>>
SPOP575710>>>>
PTPRD498242>>>>
MUC16373730>>>>
CIC331132>>>>
H3F3A310031>>>>
MUC17313120>>>>
JAK1315228>>>>
KMT2C2929140>>>>
KMT2D2929180>>>>
MYC291028>>>>
TCF12291028>>>>
TERC280028>>>>
FOXA1282840>>>>
CREB3L1261025>>>>
MIPOL1261025>>>>
SYNE1262640>>>>
SPTA1252520>>>>
RPN1241023>>>>
BCL10240024>>>>
LRP1B242430>>>>
IL2240024>>>>
EXT2243022>>>>
GATA2241023>>>>
DDB2230023>>>>
ATM222240>>>>
KDM2A202018>>>>
CSMD3202070>>>>
FAT3191910>>>>
EFNA3191018>>>>
AKAP9187211>>>>
HMCN1181810>>>>
EFNA4180018>>>>
USH2A181830>>>>
WHSC1L1184315>>>>
CCND1180018>>>>
BTG1171116>>>>
BRIP1173115>>>>
FGFR1172016>>>>
TPM3170017>>>>
MUC1170017>>>>
RYR1171700>>>>
OBSCN161600>>>>
ZFHX31616110>>>>
CACNA1E161600>>>>
RP1161610>>>>
LETM2161015>>>>
RYR2161630>>>>
AHNAK2151500>>>>
PIK3CA141400>>>>
MACF1141420>>>>
COL11A1131310>>>>
SH2B3132011>>>>
FBN3131300>>>>
ABCA13131330>>>>
KDM6A131390>>>>
CTNNB1131300>>>>
PKHD1L1131320>>>>
DCHS2131300>>>>
RYR3131330>>>>
GPR98121230>>>>
EPB41L3121200>>>>
NALCN121200>>>>
FAT2121210>>>>
FAT4121220>>>>
FBN1121220>>>>
MYO15A121200>>>>
ZMYM3121270>>>>
GRIA1121200>>>>
ALDH2121011>>>>
CSMD1121220>>>>
MUC5B121200>>>>
FLG2121210>>>>
COX18120012>>>>
DNAH3121220>>>>
SALL1121200>>>>
DNAH17121220>>>>
PKD1111120>>>>
GRIN2A111110>>>>
XIRP2111100>>>>
BAI3111100>>>>
BCL7A110011>>>>
CACNA1A111110>>>>
FCGBP111110>>>>
CNTNAP5111120>>>>
HSPG2111120>>>>
PCLO111120>>>>
APC101080>>>>
PTPN1110109>>>>
AHNAK101030>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG393674113466View
Focal adhesion - Homo sapiens (human)199KEGG32747965211View
Small cell lung cancer - Homo sapiens (human)86KEGG32725755405View
Prostate cancer - Homo sapiens (human)89KEGG32326154408View
Endometrial cancer - Homo sapiens (human)52KEGG29720347326View
Melanoma - Homo sapiens (human)71KEGG29019338324View
Glioma - Homo sapiens (human)65KEGG28318839308View
MAPK signaling pathway - Homo sapiens (human)269KEGG27941664131View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG27819036293View
Cell cycle - Homo sapiens (human)125KEGG26923553212View
p53 signaling pathway - Homo sapiens (human)68KEGG26015540259View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG2573944888View
Colorectal cancer - Homo sapiens (human)84KEGG25523542205View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG25124243179View
Olfactory transduction - Homo sapiens (human)389KEGG249424300View
Pancreatic cancer - Homo sapiens (human)72KEGG24918736215View
Tight junction - Homo sapiens (human)132KEGG24725636121View
Phosphatidylinositol signaling system - Homo sapiens (human)76KEGG24518432193View
Wnt signaling pathway - Homo sapiens (human)150KEGG24227352133View
Non-small cell lung cancer - Homo sapiens (human)54KEGG23116427187View