PCPG  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples179
No. mutated genes7216
No. SNVs2379
No. CNAs227

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
MAN1A2280028>>>>
HRAS241806>>>>
MIR4733160016>>>>
NF11515130>>>>
MAML3121012>>>>
RFX39108>>>>
TTN9900>>>>
FAT19207>>>>
ANKRD329009>>>>
ARNT9217>>>>
NUP988107>>>>
EPAS18800>>>>
MUC168800>>>>
KERA8008>>>>
TPM37007>>>>
MMRN17007>>>>
EP3007007>>>>
MCL17007>>>>
SIRT37007>>>>
PHRF17106>>>>
LMO17007>>>>
CARS7007>>>>
PDE4DIP7314>>>>
MKL16006>>>>
ABCA136600>>>>
RET6600>>>>
LINC002906006>>>>
MUC175500>>>>
FBXW75005>>>>
ATRX5530>>>>
PDGFB5005>>>>
CSDE14440>>>>
GPR1284400>>>>
CDK44004>>>>
SPHKAP4400>>>>
AHNAK4400>>>>
FLG4400>>>>
NACA4004>>>>
MYH94103>>>>
BCL94004>>>>
NOTCH24004>>>>
TYW1B3300>>>>
DENND4A3310>>>>
KCNH53310>>>>
SHROOM43300>>>>
SETD23300>>>>
CACNA1H3310>>>>
DDIT33003>>>>
FAM47C3300>>>>
OBSCN3320>>>>
ERBB33003>>>>
MAP3K43300>>>>
AMMECR13300>>>>
COL12A13300>>>>
PRUNE23300>>>>
BCOR3310>>>>
AHNAK23300>>>>
RYR13300>>>>
MLLT63300>>>>
TENM13300>>>>
VHL3300>>>>
LAMA33310>>>>
BPTF3300>>>>
HUWE13300>>>>
LYST3310>>>>
SLC35G33300>>>>
PCDHB43300>>>>
FAM83D3310>>>>
KMT2C3300>>>>
HNRNPM3300>>>>
MUC22210>>>>
ZNF6762200>>>>
CD99L22200>>>>
HMCN12200>>>>
ANAPC72210>>>>
ZEB22210>>>>
ZNF780A2200>>>>
DEPDC52200>>>>
IGDCC42210>>>>
SETBP12200>>>>
AHCTF12200>>>>
PRPF82200>>>>
CLEC17A2200>>>>
APC2200>>>>
DMBT12200>>>>
PLCH12200>>>>
NLRP62200>>>>
TRIO2200>>>>
CCT6B2200>>>>
NBPF102200>>>>
CACNA1D2200>>>>
PRMT12210>>>>
PTPN142200>>>>
GBA2200>>>>
HSPG22220>>>>
XDH2210>>>>
ZNF6132200>>>>
CMYA52200>>>>
PRICKLE22200>>>>
ANKRD30B2200>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG8999636View
MAPK signaling pathway - Homo sapiens (human)269KEGG68721914View
Focal adhesion - Homo sapiens (human)199KEGG5956711View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG5557414View
Endocytosis - Homo sapiens (human)185KEGG514839View
Renal cell carcinoma - Homo sapiens (human)70KEGG5038225View
Axon guidance - Homo sapiens (human)129KEGG494686View
Chemokine signaling pathway - Homo sapiens (human)190KEGG474476View
Melanogenesis - Homo sapiens (human)101KEGG4535513View
Tight junction - Homo sapiens (human)132KEGG4436313View
Prostate cancer - Homo sapiens (human)89KEGG4433218View
Gap junction - Homo sapiens (human)90KEGG4334411View
Insulin signaling pathway - Homo sapiens (human)137KEGG433946View
Glioma - Homo sapiens (human)65KEGG4331215View
Thyroid cancer - Homo sapiens (human)29KEGG4330013View
Melanoma - Homo sapiens (human)71KEGG4230115View
GnRH signaling pathway - Homo sapiens (human)101KEGG413846View
Long-term depression - Homo sapiens (human)72KEGG403626View
Long-term potentiation - Homo sapiens (human)70KEGG3929313View
Natural killer cell mediated cytotoxicity - Homo sapiens (human)137KEGG373226View