PAAD  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples126
No. mutated genes13831
No. SNVs29303
No. CNAs444

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
KRAS10010000>>>>
TP538181300>>>>
C9orf53440044>>>>
TTN424200>>>>
SMAD438251315>>>>
MAMLD1282800>>>>
CDKN2A2727180>>>>
FAM47C212100>>>>
MAGEC1212120>>>>
ARID1A219915>>>>
TMC4202000>>>>
IPP2020200>>>>
IRS1202010>>>>
CD99L2202000>>>>
OTUD4181800>>>>
OTOF181800>>>>
SORBS2171730>>>>
ATRX171720>>>>
MYC172217>>>>
CLTC162014>>>>
EDC4161600>>>>
C19orf55161600>>>>
CACNA1D161630>>>>
MUC17161600>>>>
THBS4161610>>>>
SLITRK5151500>>>>
SYNGAP1151500>>>>
WRN151500>>>>
EMC7151500>>>>
RP1L1141430>>>>
MST1141460>>>>
MYH10141420>>>>
RANBP2141430>>>>
DIDO1141480>>>>
TNNI3K141400>>>>
QRICH1141400>>>>
PTPRF131300>>>>
PAF1131012>>>>
MED12131300>>>>
ERF131320>>>>
NFAT5131310>>>>
TMEM1751313110>>>>
MED12L131390>>>>
CSMD2131300>>>>
FLG131340>>>>
PDZD2131310>>>>
CDH101313100>>>>
ELMSAN1131300>>>>
CCDC135131300>>>>
ZMIZ1131310>>>>
ZAN131310>>>>
CUL4B131300>>>>
RYR2131350>>>>
APP121200>>>>
GAS2L2121200>>>>
PPP2R1A12408>>>>
NBPF3121210>>>>
IFT46121200>>>>
PAK3121200>>>>
FAT112517>>>>
NPNT121200>>>>
PASD1121200>>>>
ARHGAP181212110>>>>
FCGBP121200>>>>
WWTR1121200>>>>
OR10A7121200>>>>
PRG4121200>>>>
F8121290>>>>
CLOCK121210>>>>
SEH1L121210>>>>
TTK121290>>>>
MUC16121240>>>>
MED15121200>>>>
BHLHB9121200>>>>
SETD212527>>>>
ST6GALNAC5121200>>>>
TNFSF9121200>>>>
BRDT111100>>>>
SCAF11111100>>>>
DPYS1111100>>>>
F5111100>>>>
SYT15111100>>>>
LRP1B111130>>>>
PAK1111100>>>>
SETD1A111120>>>>
RPTN111160>>>>
WHSC1L111656>>>>
LRIG1111100>>>>
PBRM111536>>>>
SBNO1111110>>>>
DNAH5111180>>>>
PHF8111100>>>>
YIPF2111100>>>>
FAM63B111100>>>>
DHX57111110>>>>
ZMYM5111100>>>>
EME2111100>>>>
CNKSR2111100>>>>
SYNE1111150>>>>
RBM10111110>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG12669616873View
MAPK signaling pathway - Homo sapiens (human)269KEGG12253810636View
Axon guidance - Homo sapiens (human)129KEGG121356482View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG1203934720View
Chemokine signaling pathway - Homo sapiens (human)190KEGG1183033510View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG1173426720View
Insulin signaling pathway - Homo sapiens (human)137KEGG1172973310View
Pancreatic cancer - Homo sapiens (human)72KEGG1173177830View
Tight junction - Homo sapiens (human)132KEGG1162843510View
T cell receptor signaling pathway - Homo sapiens (human)108KEGG1162412010View
Prostate cancer - Homo sapiens (human)89KEGG1162964834View
GnRH signaling pathway - Homo sapiens (human)101KEGG115242339View
Wnt signaling pathway - Homo sapiens (human)150KEGG1143037646View
Long-term depression - Homo sapiens (human)72KEGG1142151910View
Renal cell carcinoma - Homo sapiens (human)70KEGG1141901515View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG1143228358View
Gap junction - Homo sapiens (human)90KEGG113232202View
Natural killer cell mediated cytotoxicity - Homo sapiens (human)137KEGG1132372915View
Long-term potentiation - Homo sapiens (human)70KEGG113201202View
Progesterone-mediated oocyte maturation - Homo sapiens (human)104KEGG113244188View