OV  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples466
No. mutated genes12343
No. SNVs19577
No. CNAs8144

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP533833831230>>>>
TCF326300263>>>>
STK1126200262>>>>
MECOM25730256>>>>
MYC24900249>>>>
PIK3R117221171>>>>
PDE4D16710167>>>>
ARID1A14932148>>>>
CCNE113900139>>>>
PHRF113610135>>>>
HRAS13500135>>>>
MLLT413121130>>>>
PTPRN213030127>>>>
DPP612400124>>>>
BRD412220120>>>>
INTS412200122>>>>
MCL111900119>>>>
EZH211900119>>>>
RNF144B11300113>>>>
CARD1111010109>>>>
HPSE210920107>>>>
PMS210810108>>>>
LRP1B10714197>>>>
RB1107151094>>>>
IGF1R10210101>>>>
PPP2R2A10220100>>>>
TERT1001099>>>>
TLX1990099>>>>
ANKS1B971096>>>>
SUFU971097>>>>
PAF1950095>>>>
NFKB2940094>>>>
CBX8940094>>>>
PTEN935390>>>>
ZNF132921091>>>>
KDM5A923089>>>>
TRIM28910091>>>>
LINC00290900090>>>>
G6PD894087>>>>
NF188241866>>>>
CNTN4852083>>>>
ING5820082>>>>
WHSC1812179>>>>
MTCP1811080>>>>
FGFR3801079>>>>
LETM1800080>>>>
TTN808000>>>>
WWOX780078>>>>
SMNDC1770077>>>>
GPHN762076>>>>
KRAS755070>>>>
RAD51B750075>>>>
VTI1A741073>>>>
TCF7L2731072>>>>
FGFR2701069>>>>
CDH1682066>>>>
DMD666161>>>>
TFE3650065>>>>
KAT6A645061>>>>
GTF3C4622060>>>>
TSC1620062>>>>
ABL1611060>>>>
NUP214611060>>>>
BRD3591058>>>>
RALGDS591159>>>>
PTPRD595156>>>>
NOTCH1591058>>>>
FNBP1580058>>>>
COX18541053>>>>
FLI1540054>>>>
CREBBP5411544>>>>
PTTG1IP521051>>>>
TMPRSS2472045>>>>
U2AF1460046>>>>
JAK2451044>>>>
CD274441044>>>>
MAP2K4342132>>>>
CSMD3272710>>>>
USH2A272740>>>>
HMCN1232330>>>>
RYR2212110>>>>
FAT3202020>>>>
MUC17202020>>>>
MUC16202060>>>>
HYDIN181810>>>>
BRCA11818170>>>>
FLG161600>>>>
CDK12151570>>>>
DNAH5151530>>>>
DNAH3151520>>>>
MYH1151520>>>>
TENM1151500>>>>
SYNE1151520>>>>
TG141420>>>>
LRP2141410>>>>
SYNE2141410>>>>
AHNAK131300>>>>
APOB131310>>>>
BRCA2131390>>>>
COL6A3131320>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG4628962131945View
Prostate cancer - Homo sapiens (human)89KEGG453521153985View
Bladder cancer - Homo sapiens (human)42KEGG452444137693View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG4524811431035View
MAPK signaling pathway - Homo sapiens (human)269KEGG4516881741050View
Small cell lung cancer - Homo sapiens (human)86KEGG450578158743View
Endometrial cancer - Homo sapiens (human)52KEGG449470137853View
Colorectal cancer - Homo sapiens (human)84KEGG447486138722View
Melanoma - Homo sapiens (human)71KEGG446471144727View
Cell cycle - Homo sapiens (human)125KEGG444536157586View
Glioma - Homo sapiens (human)65KEGG444482143661View
Thyroid cancer - Homo sapiens (human)29KEGG443417131592View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG441518137436View
Non-small cell lung cancer - Homo sapiens (human)54KEGG441470141470View
Pancreatic cancer - Homo sapiens (human)72KEGG438480150394View
Wnt signaling pathway - Homo sapiens (human)150KEGG432548143365View
p53 signaling pathway - Homo sapiens (human)68KEGG420442130229View
Apoptosis - Homo sapiens (human)87KEGG418466131171View
Basal cell carcinoma - Homo sapiens (human)55KEGG409456131169View
Huntington's disease - Homo sapiens (human)179KEGG39953914144View