LUSC  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples178
No. mutated genes15078
No. SNVs47112
No. CNAs1917

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP53141141440>>>>
TTN12512500>>>>
SOX210210102>>>>
LRP1B9769747>>>>
CSMD38181200>>>>
CDKN2A81251256>>>>
MUC16767690>>>>
RYR27575100>>>>
USH2A6767100>>>>
ZFHX4656570>>>>
WHSC1L15613249>>>>
SYNE1525290>>>>
LETM2492149>>>>
NFE2L24527021>>>>
PTEN4314831>>>>
FAT142211121>>>>
RYR3414150>>>>
SPTA1393940>>>>
DNAH11393930>>>>
DMD3831610>>>>
BCL11A387034>>>>
FAM135B373740>>>>
SI363650>>>>
EYS3613426>>>>
PKHD1363650>>>>
PKHD1L1363620>>>>
KMT2D3535180>>>>
NF13521714>>>>
FLG353540>>>>
COL11A1343490>>>>
C1orf173343430>>>>
XIRP2333340>>>>
REL331033>>>>
ZNF536333330>>>>
NAV3333360>>>>
CARS328225>>>>
CUBN323220>>>>
ROBO1329125>>>>
LRP2323250>>>>
GPR98313120>>>>
HCN1313150>>>>
ING5311030>>>>
PAPPA2313130>>>>
DNAH5313180>>>>
DNAH8313160>>>>
CDH10313160>>>>
PDE4DIP312438>>>>
PHRF1305026>>>>
COL22A1303060>>>>
FOXP1304227>>>>
CSMD1303030>>>>
PAX3304026>>>>
HRAS305026>>>>
CSMD2303040>>>>
PCLO303000>>>>
MCL1292027>>>>
MUC5B292940>>>>
MUC17292930>>>>
SRSF2292027>>>>
ZNF804B292940>>>>
CNTNAP5282830>>>>
NEB282840>>>>
PARK22810120>>>>
ARNT281027>>>>
LRRC7282830>>>>
KMT2C282870>>>>
DNAH9282840>>>>
TERT283026>>>>
ADAMTS12282850>>>>
MYH2282830>>>>
RP1282840>>>>
KDM5A287122>>>>
IKZF2282126>>>>
NUP98273024>>>>
CREBBP2715212>>>>
APOB272740>>>>
PIK3CA272700>>>>
ABCA13272740>>>>
BRINP3272700>>>>
SPHKAP272710>>>>
SIRT3271026>>>>
PCDH11X272720>>>>
IL7R278022>>>>
DNAH7272740>>>>
LIFR273024>>>>
CADM2275123>>>>
ATIC271026>>>>
SLITRK3262600>>>>
MROH2B262670>>>>
FAT4262620>>>>
PCDH15262660>>>>
ACSL3262025>>>>
ANK2262610>>>>
ARID1A2612615>>>>
PXDNL252500>>>>
FEV250025>>>>
SCN1A252530>>>>
PHF3258219>>>>
RYR1252530>>>>
CPS1252520>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG1771142184295View
Focal adhesion - Homo sapiens (human)199KEGG176973118100View
MAPK signaling pathway - Homo sapiens (human)269KEGG17581913579View
Olfactory transduction - Homo sapiens (human)389KEGG17515751150View
Cell cycle - Homo sapiens (human)125KEGG174458103142View
Glioma - Homo sapiens (human)65KEGG17339389217View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG1714267458View
Colorectal cancer - Homo sapiens (human)84KEGG1713726943View
Melanoma - Homo sapiens (human)71KEGG17136086217View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG17137187167View
Wnt signaling pathway - Homo sapiens (human)150KEGG1704758222View
Prostate cancer - Homo sapiens (human)89KEGG17041582176View
Small cell lung cancer - Homo sapiens (human)86KEGG170517106100View
Non-small cell lung cancer - Homo sapiens (human)54KEGG17035081151View
Calcium signaling pathway - Homo sapiens (human)177KEGG1697859219View
Neuroactive ligand-receptor interaction - Homo sapiens (human)256KEGG169897980View
p53 signaling pathway - Homo sapiens (human)68KEGG16930381137View
Huntington's disease - Homo sapiens (human)179KEGG1694427628View
Apoptosis - Homo sapiens (human)87KEGG1683166718View
Tight junction - Homo sapiens (human)132KEGG1685117077View