LUAD  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples533
No. mutated genes17517
No. SNVs142257
No. CNAs3314

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP532802801030>>>>
TTN25825800>>>>
MUC16223223400>>>>
CSMD3212212520>>>>
LRP1B2081874435>>>>
RYR2204204370>>>>
KRAS186161148>>>>
USH2A173173300>>>>
ZFHX4161161290>>>>
CSMD11411181933>>>>
XIRP2141141240>>>>
SPTA1130130250>>>>
FLG128128140>>>>
SFTA311310112>>>>
CDKN2A11319596>>>>
NAV3110110130>>>>
MUC17108108100>>>>
FAT3107107150>>>>
ZNF536107107200>>>>
PCLO107107170>>>>
COL11A1106106200>>>>
ANK2105105110>>>>
APOB10410450>>>>
PCDH1510110190>>>>
PAPPA29696150>>>>
ADAMTS129595160>>>>
RP1L19494110>>>>
ARNT945390>>>>
GPR1129292130>>>>
SI9191150>>>>
TERT917087>>>>
KEAP19191200>>>>
RYR39191100>>>>
ZNF804A8989170>>>>
PTPRD8888150>>>>
FAT188561236>>>>
CDH108888150>>>>
TNR8888150>>>>
MIR1208880088>>>>
DNAH98787180>>>>
RYR18787110>>>>
EGFR8670333>>>>
KMT2C8585110>>>>
FAM135B8585110>>>>
C1orf1738484120>>>>
NRXN18383140>>>>
FBN28383170>>>>
MXRA5838380>>>>
DMD8282190>>>>
NPAP1828260>>>>
CACNA1E8282110>>>>
PXDNL8181110>>>>
RELN8181120>>>>
OBSCN8080100>>>>
FAT4808060>>>>
HMCN17979210>>>>
NALCN7878120>>>>
AHNAK2787860>>>>
VCAN7878140>>>>
CSMD27777120>>>>
LRRC77777180>>>>
FLG2777770>>>>
STK117777560>>>>
PCDH11X7676100>>>>
ASTN17474120>>>>
HRNR7474120>>>>
TSHZ37373120>>>>
CNTNAP27373110>>>>
NEB7272180>>>>
ABCA137272130>>>>
TG7272110>>>>
RIMS27272120>>>>
PKHD1717160>>>>
AHNAK707080>>>>
PRDM97070140>>>>
CNTNAP5696990>>>>
DNAH56969140>>>>
ASPM696940>>>>
LRP2696940>>>>
PKHD1L16969110>>>>
BRINP36868120>>>>
TNN6868140>>>>
ZNF831676770>>>>
SYNE16767150>>>>
ASXL3666690>>>>
LAMA26666120>>>>
FAM47C6666110>>>>
LPHN36666120>>>>
EPHA56666140>>>>
COL6A3656560>>>>
MYH2656580>>>>
ZNF52164521118>>>>
PRUNE2646430>>>>
DOCK2646490>>>>
SORCS1646490>>>>
UNC79636390>>>>
MYH8636360>>>>
CPS1636390>>>>
NOTCH26223539>>>>
MYH16262150>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG5173391552743View
MAPK signaling pathway - Homo sapiens (human)269KEGG5072476396218View
Focal adhesion - Homo sapiens (human)199KEGG4982952450198View
Prostate cancer - Homo sapiens (human)89KEGG4981191222408View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG495973200522View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG4922090269172View
Pancreatic cancer - Homo sapiens (human)72KEGG4921052205376View
Glioma - Homo sapiens (human)65KEGG4921057192397View
Melanoma - Homo sapiens (human)71KEGG4911036191420View
Non-small cell lung cancer - Homo sapiens (human)54KEGG489947173377View
Bladder cancer - Homo sapiens (human)42KEGG487799164396View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG4861264213243View
Endometrial cancer - Homo sapiens (human)52KEGG486978165259View
Olfactory transduction - Homo sapiens (human)389KEGG48448634880View
Colorectal cancer - Homo sapiens (human)84KEGG4831200200216View
Calcium signaling pathway - Homo sapiens (human)177KEGG477254433056View
Cell cycle - Homo sapiens (human)125KEGG4641065262403View
Axon guidance - Homo sapiens (human)129KEGG4641822254142View
Gap junction - Homo sapiens (human)90KEGG4611181126152View
Tight junction - Homo sapiens (human)132KEGG4581507193185View