LIHC  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples373
No. mutated genes15157
No. SNVs39299
No. CNAs2590

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP531231124234>>>>
TTN10010000>>>>
CTNNB1979720>>>>
ARID1A82312359>>>>
PRDM16795174>>>>
RPL22781177>>>>
RB174211764>>>>
MYC712069>>>>
EXT1701070>>>>
NDRG1681068>>>>
LINC00536660066>>>>
LRP1B6232435>>>>
PAX7572055>>>>
SDHB541053>>>>
MUC16545480>>>>
CDKN2A5310443>>>>
MDS2530053>>>>
SMYD3482046>>>>
LCK484144>>>>
TERT442043>>>>
ALB4343300>>>>
FH422040>>>>
VEGFA402138>>>>
APOB3939200>>>>
PER1395134>>>>
TNFSF10371036>>>>
GPHN376131>>>>
CCND1371036>>>>
RYR2373760>>>>
ERCC5354132>>>>
PCLO353550>>>>
PTEN3410527>>>>
GNA11330033>>>>
CSMD3333370>>>>
TDRD9337226>>>>
TCF3332032>>>>
MAP2K2332031>>>>
ABCA13323260>>>>
STK11321132>>>>
NEDD9322130>>>>
GAS7312130>>>>
SH3GL1312130>>>>
BCL11B318224>>>>
OBSCN303020>>>>
WWOX301029>>>>
FSTL3300030>>>>
CACNA1E303030>>>>
USP6304226>>>>
RYR1303050>>>>
XIRP2292950>>>>
FGFR2293026>>>>
DICER1296223>>>>
FOXP1293027>>>>
TCF7L2293126>>>>
BRD4286122>>>>
ARHGEF12287221>>>>
VTI1A282127>>>>
AKT1281127>>>>
AKAP8274123>>>>
ATM279118>>>>
SPTA1272740>>>>
HMCN1272780>>>>
YWHAE271026>>>>
SETD3262124>>>>
AHNAK2262620>>>>
CBL264122>>>>
FAT3252520>>>>
AOX2P250025>>>>
USH2A252550>>>>
FLG252520>>>>
FRAS1252540>>>>
RXRA252023>>>>
CEBPA254021>>>>
GPR98242460>>>>
PCSK7243021>>>>
ING5242222>>>>
TCL6240024>>>>
BCL7A242122>>>>
TCL1A240024>>>>
ALMS1242430>>>>
AXIN12424210>>>>
DNAH6232350>>>>
DNAH7232360>>>>
G6PD221122>>>>
CUBN222220>>>>
ARID22222150>>>>
SMNDC1222020>>>>
DDX6221021>>>>
PAFAH1B2221121>>>>
FLI1222020>>>>
CSMD1222250>>>>
POU2AF1224018>>>>
EYS222240>>>>
SYNE1222230>>>>
SMAD4214118>>>>
MET212019>>>>
BIRC6212130>>>>
KMT2D212180>>>>
BAP12121140>>>>
DNAH9212100>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG3541187274579View
Focal adhesion - Homo sapiens (human)199KEGG318871161162View
Colorectal cancer - Homo sapiens (human)84KEGG317462113244View
MAPK signaling pathway - Homo sapiens (human)269KEGG316749167187View
Wnt signaling pathway - Homo sapiens (human)150KEGG309567135183View
Prostate cancer - Homo sapiens (human)89KEGG309502120286View
Endometrial cancer - Homo sapiens (human)52KEGG304397108250View
Cell cycle - Homo sapiens (human)125KEGG291419126308View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG29032194344View
Small cell lung cancer - Homo sapiens (human)86KEGG288456129295View
Glioma - Homo sapiens (human)65KEGG277323103262View
Bladder cancer - Homo sapiens (human)42KEGG27724079315View
Pancreatic cancer - Homo sapiens (human)72KEGG27432995260View
Thyroid cancer - Homo sapiens (human)29KEGG27227561219View
Calcium signaling pathway - Homo sapiens (human)177KEGG27165811333View
Melanoma - Homo sapiens (human)71KEGG26929998281View
Huntington's disease - Homo sapiens (human)179KEGG26744199107View
Olfactory transduction - Homo sapiens (human)389KEGG264704950View
Non-small cell lung cancer - Homo sapiens (human)54KEGG26428194258View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG25856510078View