KIRP  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples282
No. mutated genes11488
No. SNVs13818
No. CNAs288

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TTN343400>>>>
MET292108>>>>
MUC16242440>>>>
ARID1A218414>>>>
PRDM16192017>>>>
CAMTA1192117>>>>
KMT2C1818100>>>>
RPL22181117>>>>
KIAA1109161630>>>>
CDKN2A161115>>>>
SETD21616120>>>>
PAX7151014>>>>
DDX10154011>>>>
ATM14529>>>>
SDHB140014>>>>
MDS2140014>>>>
AR131300>>>>
KMT2D131330>>>>
BAP1131350>>>>
PKHD1131310>>>>
CUBN121220>>>>
FAT1121260>>>>
WDFY3121240>>>>
DNAH8121200>>>>
PCLO111110>>>>
OBSCN111130>>>>
PCF11111100>>>>
LRP2111150>>>>
PBRM1111180>>>>
POU2AF111209>>>>
MUC2111100>>>>
SYNE1111100>>>>
CUL3101070>>>>
KDM6A101090>>>>
SDHD10109>>>>
NF2101090>>>>
SMARCA4101010>>>>
HELZ2101010>>>>
GPR989910>>>>
ZNF8149930>>>>
PCSK79108>>>>
SRRM29920>>>>
BIRC39208>>>>
ARHGEF129207>>>>
PAFAH1B29108>>>>
HERC29900>>>>
UBR49920>>>>
MUC179910>>>>
ANK39930>>>>
SYNE29930>>>>
SRCAP9920>>>>
MKI678830>>>>
DDX68008>>>>
SPATA31D18810>>>>
HERC18820>>>>
CSMD38840>>>>
MUC5B8820>>>>
USH2A8800>>>>
ALMS18810>>>>
DNAH18810>>>>
GBF18810>>>>
CNTNAP58810>>>>
BOD1L18820>>>>
NIPBL8850>>>>
TET18820>>>>
CREBBP8810>>>>
WDR818830>>>>
CENPF8830>>>>
MACF18800>>>>
ABCA78800>>>>
MICAL37720>>>>
PTEN7750>>>>
APOB7720>>>>
LRBA7740>>>>
C5orf427700>>>>
FANCA7205>>>>
BIRC67720>>>>
CNOT17730>>>>
ATP1B17720>>>>
UNC13A7700>>>>
NCOR17710>>>>
JMJD1C7710>>>>
STAG27760>>>>
SF3B17700>>>>
TP537710>>>>
ANK27730>>>>
CBL7007>>>>
RYR17710>>>>
IGF2R6610>>>>
BCLAF16630>>>>
AHNAK6630>>>>
CLTC6610>>>>
SHANK36600>>>>
RAI16610>>>>
MON26620>>>>
MPRIP6620>>>>
SPTA16610>>>>
FNIP26620>>>>
LRP1B6600>>>>
UBR36610>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG2063546238View
Focal adhesion - Homo sapiens (human)199KEGG1652675216View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG149219337View
MAPK signaling pathway - Homo sapiens (human)269KEGG133206430View
Calcium signaling pathway - Homo sapiens (human)177KEGG133185360View
Endocytosis - Homo sapiens (human)185KEGG1301723515View
Huntington's disease - Homo sapiens (human)179KEGG1251353023View
Ubiquitin mediated proteolysis - Homo sapiens (human)133KEGG1241534115View
Axon guidance - Homo sapiens (human)129KEGG1231472715View
Dilated cardiomyopathy - Homo sapiens (human)90KEGG115146240View
Olfactory transduction - Homo sapiens (human)389KEGG112151190View
Tight junction - Homo sapiens (human)132KEGG110147300View
ECM-receptor interaction - Homo sapiens (human)84KEGG109136250View
Cytokine-cytokine receptor interaction - Homo sapiens (human)262KEGG108130188View
Insulin signaling pathway - Homo sapiens (human)137KEGG108133187View
Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)83KEGG108139230View
Wnt signaling pathway - Homo sapiens (human)150KEGG105139310View
Alzheimer's disease - Homo sapiens (human)166KEGG1051152523View
Neuroactive ligand-receptor interaction - Homo sapiens (human)256KEGG103138190View
Colorectal cancer - Homo sapiens (human)84KEGG102118178View