KIRC  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples436
No. mutated genes12587
No. SNVs19191
No. CNAs1934

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
VHL24021511969>>>>
PBRM11251251010>>>>
NSD110462101>>>>
PRELID110210101>>>>
RANBP171001099>>>>
TLX3980098>>>>
NPM1980098>>>>
EBF1950095>>>>
XPC714068>>>>
SRGAP3713068>>>>
FANCD2690069>>>>
PPARG691068>>>>
RAF1680068>>>>
MLH1672165>>>>
CNTN4660066>>>>
TTN626200>>>>
SETD24444300>>>>
BAP13636250>>>>
MUC16363600>>>>
ARID1A3510726>>>>
MTOR303000>>>>
ING5290029>>>>
CAMTA1273024>>>>
KDM5C2626170>>>>
PARK2250025>>>>
RPL22252123>>>>
MLLT4245219>>>>
PIK3CA2410115>>>>
SDHB231022>>>>
MDS2230023>>>>
PAX7220022>>>>
ECT2L212019>>>>
ROS1217114>>>>
PRDM16200020>>>>
PTEN2015108>>>>
TNFAIP3200020>>>>
CDKN2A203118>>>>
EZR190019>>>>
MYB191018>>>>
FGFR1OP190019>>>>
ROBO1181117>>>>
NEGR1182016>>>>
BRCA2175012>>>>
HMCN1171740>>>>
SYNE1171730>>>>
BCL6165111>>>>
FAT116709>>>>
KMT2C161680>>>>
AHNAK2161630>>>>
GOPC161015>>>>
GPR98141430>>>>
TFRC142112>>>>
EIF4A2143011>>>>
USH2A141450>>>>
DNAH9141420>>>>
HDAC2140014>>>>
CADM2142012>>>>
PCLO131320>>>>
SPEN131330>>>>
LRP2131330>>>>
TERC130013>>>>
SOX2130013>>>>
ATM121270>>>>
BDH1120012>>>>
LHFP120012>>>>
CSMD3121230>>>>
CDX2122210>>>>
XIRP2121220>>>>
ABCA13121210>>>>
CSMD1121230>>>>
DST121210>>>>
DNAH2121210>>>>
GPHN122110>>>>
LPP122011>>>>
MAGEC1121210>>>>
FLT3122010>>>>
ANK3121220>>>>
RB1121011>>>>
BCL11B122010>>>>
MPHOSPH8112010>>>>
SPTA1111110>>>>
LRP1B111110>>>>
FBN2111130>>>>
LCP1110011>>>>
COL6A6111140>>>>
RYR1111110>>>>
ETV5110011>>>>
AKAP9101020>>>>
NEB101010>>>>
SMARCA4101020>>>>
KMT2D101020>>>>
FLG101010>>>>
HUWE1101000>>>>
SETD310109>>>>
PKHD1L1101020>>>>
RAD51B100010>>>>
CHD79900>>>>
ADAMTS209930>>>>
SLITRK69920>>>>
FBXW79108>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG387708196371View
Ubiquitin mediated proteolysis - Homo sapiens (human)133KEGG313402154102View
Renal cell carcinoma - Homo sapiens (human)70KEGG290305129165View
Focal adhesion - Homo sapiens (human)199KEGG2733997498View
MAPK signaling pathway - Homo sapiens (human)269KEGG2513165875View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG24228744102View
Calcium signaling pathway - Homo sapiens (human)177KEGG210292460View
Chemokine signaling pathway - Homo sapiens (human)190KEGG2051812290View
Prostate cancer - Homo sapiens (human)89KEGG20016323109View
Insulin signaling pathway - Homo sapiens (human)137KEGG1991952390View
Huntington's disease - Homo sapiens (human)179KEGG19614819104View
Axon guidance - Homo sapiens (human)129KEGG1931803285View
Glioma - Homo sapiens (human)65KEGG18713021127View
Olfactory transduction - Homo sapiens (human)389KEGG185270370View
Neuroactive ligand-receptor interaction - Homo sapiens (human)256KEGG184236328View
Vascular smooth muscle contraction - Homo sapiens (human)115KEGG1841683468View
Fc gamma R-mediated phagocytosis - Homo sapiens (human)96KEGG1801311890View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG1801502090View
Progesterone-mediated oocyte maturation - Homo sapiens (human)104KEGG1791422290View
ErbB signaling pathway - Homo sapiens (human)87KEGG1731381390View