HNSC  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples511
No. mutated genes16752
No. SNVs74209
No. CNAs3741

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP533603601640>>>>
CDKN2A27210482176>>>>
TTN21321300>>>>
LRP1B1738612109>>>>
FAT11711129177>>>>
SOX215641153>>>>
NOTCH1111903922>>>>
CSMD3105105230>>>>
MUC16101101170>>>>
PIK3CA949410>>>>
SYNE19090120>>>>
PAX3836077>>>>
NOTCH281211061>>>>
KMT2D8181550>>>>
ACSL3803177>>>>
PCLO808070>>>>
NSD178624221>>>>
ATIC775072>>>>
ING5763374>>>>
FLG7474140>>>>
EGFR7419261>>>>
MPHOSPH8727166>>>>
FEV720072>>>>
NFE2L27227151>>>>
DNAH57070150>>>>
TRIM33674064>>>>
EZH2665061>>>>
PDE4D666060>>>>
USH2A6565110>>>>
NRAS641063>>>>
STK11644262>>>>
FAM46C644060>>>>
RB164171250>>>>
LCP16014047>>>>
RYR2606080>>>>
HRAS5931128>>>>
PCSK7582056>>>>
POU2AF1580058>>>>
SDHD570057>>>>
PAFAH1B2560056>>>>
XIRP2555530>>>>
CASP85454290>>>>
WWOX537346>>>>
PKHD1L15353120>>>>
SI5252130>>>>
PARD35113338>>>>
LETM2503148>>>>
AHNAK494980>>>>
COL11A14949150>>>>
DMD494970>>>>
FAM135B494920>>>>
IMMP2L491048>>>>
WHSC1L1495147>>>>
FGFR1482046>>>>
HUWE1464670>>>>
EYS4619329>>>>
PHRF14517028>>>>
PAPPA2454550>>>>
RELN454580>>>>
PCDH15454550>>>>
DNAH9454570>>>>
CHD84418526>>>>
APOB444450>>>>
FAT3444460>>>>
TERT443041>>>>
PTEN4314831>>>>
FAT4434300>>>>
PHF34318227>>>>
CAMTA14315430>>>>
KMT2C4242150>>>>
MUC17424240>>>>
LAMA2414140>>>>
PTPRG418133>>>>
ZFHX4414140>>>>
PLEC414160>>>>
KDM5A416135>>>>
ARID1A4119725>>>>
PRDM164010130>>>>
GPR98404050>>>>
CUBN404060>>>>
CDK6401140>>>>
MUC5B404020>>>>
DNAH8404080>>>>
JAK2405135>>>>
COL22A1393990>>>>
DNAH7393930>>>>
DNAH11393950>>>>
EP300383890>>>>
VPS13B373770>>>>
CD274371036>>>>
G6PD374033>>>>
NAV3373720>>>>
PCDH11X373720>>>>
UNC13C3737100>>>>
LRP2373710>>>>
RP1373740>>>>
SYNE2373740>>>>
NEB363620>>>>
FMN2363620>>>>
DST3535100>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG5052359519549View
Glioma - Homo sapiens (human)65KEGG491914299488View
Melanoma - Homo sapiens (human)71KEGG490876299534View
Prostate cancer - Homo sapiens (human)89KEGG489950251333View
Non-small cell lung cancer - Homo sapiens (human)54KEGG488859292449View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG487927311396View
MAPK signaling pathway - Homo sapiens (human)269KEGG4851555320214View
Pancreatic cancer - Homo sapiens (human)72KEGG479935324358View
Endometrial cancer - Homo sapiens (human)52KEGG478798217214View
Cell cycle - Homo sapiens (human)125KEGG473956327289View
Small cell lung cancer - Homo sapiens (human)86KEGG469992257137View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG467955225107View
Bladder cancer - Homo sapiens (human)42KEGG467669276416View
Focal adhesion - Homo sapiens (human)199KEGG4661590208151View
Huntington's disease - Homo sapiens (human)179KEGG46395227387View
Colorectal cancer - Homo sapiens (human)84KEGG46390823477View
Wnt signaling pathway - Homo sapiens (human)150KEGG462108026626View
Apoptosis - Homo sapiens (human)87KEGG45376423316View
p53 signaling pathway - Homo sapiens (human)68KEGG442726317270View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG4411138136198View