DLBC  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples48
No. mutated genes10125
No. SNVs9944
No. CNAs229

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
IGLL5171760>>>>
CDKN2A170017>>>>
TNFAIP314658>>>>
KMT2D1414120>>>>
BTG2131330>>>>
LRP1B13727>>>>
REL132011>>>>
MUC2121200>>>>
PRDM1124210>>>>
FAT111714>>>>
MUC16111100>>>>
B2M101040>>>>
FAT4101010>>>>
TTN101000>>>>
CARD11101000>>>>
SYNE1101010>>>>
PIM1101020>>>>
PRDM139009>>>>
HIST1H1E9910>>>>
CIITA9545>>>>
PCLO8810>>>>
P2RY88800>>>>
CSMD38810>>>>
MUC5B8800>>>>
MYC8305>>>>
RHPN27700>>>>
BTG17730>>>>
ATM7700>>>>
OBSCN7700>>>>
ZNF8147700>>>>
ZFHX47710>>>>
DMBT17700>>>>
HIST1H1C7710>>>>
HLA-C7710>>>>
MYD887700>>>>
LRP27700>>>>
SUV420H27106>>>>
EZH27304>>>>
KLHL67700>>>>
STAT37700>>>>
ARHGAP216620>>>>
H3F3A6105>>>>
EBF16105>>>>
ACACB6600>>>>
PARP106006>>>>
ASXL36620>>>>
SMYD36105>>>>
IRF46600>>>>
PCDHA106600>>>>
HMCN16600>>>>
CYC16006>>>>
KMT2C6600>>>>
CSMD16600>>>>
GABRG36600>>>>
USH2A6600>>>>
BRAF6303>>>>
MUC176600>>>>
TMSB4X6610>>>>
FH6006>>>>
LAMA16600>>>>
TET26650>>>>
CREBBP6610>>>>
ZNF2086600>>>>
COL21A16610>>>>
VCAN6600>>>>
NDRG15104>>>>
PKD15500>>>>
KIAA15495203>>>>
GPR985500>>>>
SPEN5530>>>>
FLG5510>>>>
ELAVL15104>>>>
PXDNL5500>>>>
PCDHA45500>>>>
IRF85510>>>>
NOTCH25431>>>>
CD79B5500>>>>
HIST1H1D5500>>>>
PDE4DIP5510>>>>
SPHKAP5500>>>>
PDE3A5510>>>>
HLA-A5530>>>>
XIRP25500>>>>
ZNF1895500>>>>
FAS5520>>>>
SCN7A5510>>>>
EXT15104>>>>
ITPKB5520>>>>
SCN9A5520>>>>
CACNA1H5500>>>>
UBR45510>>>>
SOCS15520>>>>
MTUS15500>>>>
DST5500>>>>
PCDH175500>>>>
TIAM25500>>>>
TPR5401>>>>
MYO18B5500>>>>
DNAH55510>>>>
DNAH95500>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG472311544View
MAPK signaling pathway - Homo sapiens (human)269KEGG451561212View
Cell cycle - Homo sapiens (human)125KEGG4478827View
Wnt signaling pathway - Homo sapiens (human)150KEGG4193105View
Olfactory transduction - Homo sapiens (human)389KEGG41208140View
Focal adhesion - Homo sapiens (human)199KEGG4018443View
Jak-STAT signaling pathway - Homo sapiens (human)155KEGG40105105View
Bladder cancer - Homo sapiens (human)42KEGG4042432View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG4051732View
Pancreatic cancer - Homo sapiens (human)72KEGG3954525View
Neuroactive ligand-receptor interaction - Homo sapiens (human)256KEGG3814290View
Endocytosis - Homo sapiens (human)185KEGG3896124View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG3813695View
Melanoma - Homo sapiens (human)71KEGG3847527View
Glioma - Homo sapiens (human)65KEGG3745527View
Non-small cell lung cancer - Homo sapiens (human)54KEGG3741527View
Cytokine-cytokine receptor interaction - Homo sapiens (human)262KEGG36121130View
p53 signaling pathway - Homo sapiens (human)68KEGG3634718View
Tight junction - Homo sapiens (human)132KEGG3610562View
Calcium signaling pathway - Homo sapiens (human)177KEGG35111100View