COAD  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples367
No. mutated genes17792
No. SNVs137325
No. CNAs1184

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
APC30029526034>>>>
TTN23123100>>>>
TP53230230640>>>>
PIK3CA175175110>>>>
KRAS16816800>>>>
PTEN1671533525>>>>
SMAD41351191726>>>>
RBFOX1134152124>>>>
ATM132132370>>>>
SYNE1118118190>>>>
ARID1A115723547>>>>
MUC16105105190>>>>
FBXW7102102260>>>>
KIT969650>>>>
BRAF969680>>>>
PTCH18888180>>>>
NF18888250>>>>
RB18787250>>>>
CSMD38585170>>>>
FAT48585160>>>>
RYR28484150>>>>
LRP1B8282190>>>>
HYDIN8080100>>>>
CSMD17752926>>>>
LRP27777150>>>>
PARK27610366>>>>
DNAH57575160>>>>
USH2A747480>>>>
EGFR747440>>>>
CDH17474210>>>>
CTNNB1737340>>>>
OBSCN717160>>>>
HMCN1707090>>>>
RELN656560>>>>
FLG646460>>>>
PRKDC6363150>>>>
RYR3636390>>>>
VHL626240>>>>
NF26262250>>>>
DNAH116262150>>>>
GPR986161130>>>>
TENM1616180>>>>
SDK1606050>>>>
CREBBP6060110>>>>
DNAH85959130>>>>
KMT2C5858150>>>>
NEB575780>>>>
PKHD1575780>>>>
EPHA3565660>>>>
ZFHX45656100>>>>
DST5555120>>>>
APOB5454110>>>>
ABCA135454110>>>>
FHIT541054>>>>
ANK2545490>>>>
MDN15353100>>>>
PCLO5353160>>>>
DMD5252140>>>>
VPS13B525280>>>>
KMT2D5252100>>>>
DNAH25252120>>>>
XIRP25151130>>>>
COL6A3515150>>>>
TOP15111440>>>>
AMER15050340>>>>
BRCA24949130>>>>
CUBN494980>>>>
FMN2494960>>>>
LRRK2494990>>>>
COL12A1494970>>>>
TRRAP484860>>>>
SACS4848140>>>>
BCL2L1481047>>>>
ANK34848190>>>>
CHD14723524>>>>
ERBB4474750>>>>
PDGFRA474760>>>>
LAMA1474720>>>>
ROS14747210>>>>
MLH14747120>>>>
RYR1474720>>>>
ERBB24627023>>>>
CSMD2464630>>>>
FAT3464680>>>>
ABCA124646120>>>>
MACF1464640>>>>
CACNA1E464650>>>>
RNF434646360>>>>
MUC17464630>>>>
DCHS24646100>>>>
FAT2454550>>>>
MYCBP2454590>>>>
COL6A6454520>>>>
STK114531815>>>>
SCN2A454540>>>>
DNAH34545130>>>>
NBEA454590>>>>
COL11A1444480>>>>
FGFR2444450>>>>
PCDH15444470>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG36750751029234View
Endometrial cancer - Homo sapiens (human)52KEGG3651850511121View
Wnt signaling pathway - Homo sapiens (human)150KEGG3641836547138View
Colorectal cancer - Homo sapiens (human)84KEGG3642101529108View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG362271056934View
MAPK signaling pathway - Homo sapiens (human)269KEGG361279743371View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG3601552240152View
Prostate cancer - Homo sapiens (human)89KEGG358190927870View
Pancreatic cancer - Homo sapiens (human)72KEGG3571534241136View
Basal cell carcinoma - Homo sapiens (human)55KEGG357111343234View
Glioma - Homo sapiens (human)65KEGG356151522234View
Melanoma - Homo sapiens (human)71KEGG354157624034View
Small cell lung cancer - Homo sapiens (human)86KEGG3521574288187View
Non-small cell lung cancer - Homo sapiens (human)54KEGG352126917886View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG351161721522View
Thyroid cancer - Homo sapiens (human)29KEGG34988114139View
Bladder cancer - Homo sapiens (human)42KEGG348101415071View
Focal adhesion - Homo sapiens (human)199KEGG347306343578View
Cell cycle - Homo sapiens (human)125KEGG3441490307128View
ErbB signaling pathway - Homo sapiens (human)87KEGG339139716072View