CHOL  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples35
No. mutated genes8072
No. SNVs4192
No. CNAs283

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
SDHB250025>>>>
PAX7250025>>>>
ARID1A255525>>>>
MDS2250025>>>>
BAP111865>>>>
PBRM111875>>>>
MUC19009>>>>
CDKN2A9207>>>>
TTN8800>>>>
LINC002908008>>>>
MUC27700>>>>
SETD27216>>>>
FGFR27205>>>>
KMT2C7750>>>>
FOXP16006>>>>
MLH16105>>>>
CNTN46105>>>>
DNAH56620>>>>
XPC5005>>>>
MUC5B5510>>>>
NFKB25213>>>>
PPARG5005>>>>
GPR985500>>>>
ATM5303>>>>
AHNAK5500>>>>
ABCA135510>>>>
TP535510>>>>
HLA-B5500>>>>
RAF15005>>>>
MYD885005>>>>
CDC275500>>>>
RYR35500>>>>
HPSE25104>>>>
MUC165510>>>>
BIRC65500>>>>
PAFAH1B25203>>>>
CADM25104>>>>
VHL5005>>>>
POLE5510>>>>
CTNNB15005>>>>
SRGAP35005>>>>
MITF5005>>>>
FANCD25005>>>>
PLXNA45500>>>>
TCHH5500>>>>
FHIT4004>>>>
CLIP44410>>>>
APC4420>>>>
PRG44400>>>>
COL6A34400>>>>
FAT14400>>>>
DDX104103>>>>
IDH14400>>>>
DMXL24400>>>>
KIAA11094420>>>>
DDHD14400>>>>
VTI1A4004>>>>
ANKRD174400>>>>
OTOP14400>>>>
FMN24410>>>>
EP4004400>>>>
HTT4410>>>>
AHNAK24400>>>>
PKHD1L14400>>>>
PAXIP14410>>>>
SMG14400>>>>
SMNDC14004>>>>
GLG14400>>>>
FLI14004>>>>
EPHA24420>>>>
CCND14004>>>>
ARID1B4410>>>>
TCF7L24004>>>>
RAD54L24410>>>>
NLRP84410>>>>
KIF1B4400>>>>
LRP1B4400>>>>
NAV34410>>>>
MUC63300>>>>
ZNF6763300>>>>
ARHGEF123003>>>>
PLEKHH33300>>>>
MDN13300>>>>
CSMD23310>>>>
CSMD13310>>>>
SMARCA53320>>>>
CACNA1E3310>>>>
DLGAP23300>>>>
ZNF1003300>>>>
NAP1L13300>>>>
UBR13300>>>>
HMCN13300>>>>
CHD73310>>>>
ITPR23310>>>>
NCOR13300>>>>
TEK3300>>>>
TLX13003>>>>
TRAF43300>>>>
GRIN2D3300>>>>
DST3300>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG351272060View
Huntington's disease - Homo sapiens (human)179KEGG3435533View
MAPK signaling pathway - Homo sapiens (human)269KEGG3367913View
Focal adhesion - Homo sapiens (human)199KEGG3282615View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG3273613View
Alzheimer's disease - Homo sapiens (human)166KEGG3148628View
Colorectal cancer - Homo sapiens (human)84KEGG3135523View
Calcium signaling pathway - Homo sapiens (human)177KEGG3073110View
Oxidative phosphorylation - Homo sapiens (human)130KEGG2911228View
Wnt signaling pathway - Homo sapiens (human)150KEGG2937913View
Progesterone-mediated oocyte maturation - Homo sapiens (human)104KEGG293715View
Endometrial cancer - Homo sapiens (human)52KEGG2934424View
Prostate cancer - Homo sapiens (human)89KEGG2939424View
Citrate cycle (TCA cycle) - Homo sapiens (human)31KEGG2811028View
Olfactory transduction - Homo sapiens (human)389KEGG286530View
Parkinson's disease - Homo sapiens (human)127KEGG2810128View
Glioma - Homo sapiens (human)65KEGG2833517View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG2829419View
SWI/SNF; SWI/SNF; hSWI/SNF; BAF11PINdb2814725View
Cell cycle - Homo sapiens (human)125KEGG2741614View