CESC  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples194
No. mutated genes13934
No. SNVs27607
No. CNAs1789

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TTN626200>>>>
PIK3CA535300>>>>
TERC470047>>>>
LRP1B4613235>>>>
ATM4511235>>>>
ING5431042>>>>
ARHGEF12405235>>>>
PCSK7395034>>>>
FLI1371036>>>>
CBL361035>>>>
PAFAH1B2351034>>>>
POU2AF1340034>>>>
DDX6340034>>>>
DDX10340034>>>>
SDHD330033>>>>
RB1339526>>>>
FAT12910620>>>>
KMT2C2929210>>>>
MYC291029>>>>
PTEN28151115>>>>
BIRC3281027>>>>
MUC16282830>>>>
GPR98262600>>>>
ARID1A2614912>>>>
MPHOSPH8252023>>>>
ING1252123>>>>
LCP1240024>>>>
STK11245122>>>>
WWOX235018>>>>
G6PD231022>>>>
MTCP1230023>>>>
ERCC5232021>>>>
SYNE1232340>>>>
KMT2D2222160>>>>
NFE2L22212211>>>>
EP3002121100>>>>
RYR2212120>>>>
DMD202030>>>>
PRDM16204016>>>>
MLLT4205115>>>>
ARNT202118>>>>
FLG202030>>>>
SYNE2202010>>>>
MCL1191018>>>>
PARK2192017>>>>
FBXW7191950>>>>
CAMTA1194015>>>>
ERBB2181008>>>>
EZR186013>>>>
USH2A181820>>>>
TERT181017>>>>
FHIT170017>>>>
EFNA4170017>>>>
EFNA3170017>>>>
BCL2L1170017>>>>
SF3B1171016>>>>
KIAA1549165011>>>>
OBSCN161620>>>>
NEB161620>>>>
HMCN1161640>>>>
HLA-A1616130>>>>
TRIP11167110>>>>
MUC1160016>>>>
MDN1161600>>>>
APOB151500>>>>
PCLO151530>>>>
TPM3150015>>>>
RPL22150015>>>>
EZH2153012>>>>
PDE4D150015>>>>
SMAD414727>>>>
PTPN1314618>>>>
CD274141013>>>>
FGFR1OP140014>>>>
ABCA12141460>>>>
NAV3141410>>>>
GOLGB1141410>>>>
LRP2141410>>>>
CSMD1141440>>>>
MUC5B141430>>>>
DST141430>>>>
FOXK2141013>>>>
DNAH6141400>>>>
CREBBP131340>>>>
PHRF113508>>>>
CHN1132011>>>>
ASPSCR1131012>>>>
FAT3131310>>>>
RFNG131012>>>>
CREB3L2131012>>>>
DICER1133110>>>>
CSMD3131330>>>>
PMS1132111>>>>
BRAF132111>>>>
MUC17131330>>>>
DNAH2131320>>>>
DNAH3131330>>>>
PLEC131320>>>>
CRTC3132011>>>>
AKT112309>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG187691101268View
Focal adhesion - Homo sapiens (human)199KEGG1695246798View
MAPK signaling pathway - Homo sapiens (human)269KEGG1604444180View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG1584245084View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG15820320151View
Prostate cancer - Homo sapiens (human)89KEGG15727540118View
Small cell lung cancer - Homo sapiens (human)86KEGG15724042140View
ErbB signaling pathway - Homo sapiens (human)87KEGG15222810123View
Cell cycle - Homo sapiens (human)125KEGG15021943108View
Insulin signaling pathway - Homo sapiens (human)137KEGG1502982472View
Endometrial cancer - Homo sapiens (human)52KEGG1491922197View
Jak-STAT signaling pathway - Homo sapiens (human)155KEGG1452783990View
Colorectal cancer - Homo sapiens (human)84KEGG1452202376View
Glioma - Homo sapiens (human)65KEGG1431952198View
Melanoma - Homo sapiens (human)71KEGG1431782498View
Non-small cell lung cancer - Homo sapiens (human)54KEGG1421771396View
Axon guidance - Homo sapiens (human)129KEGG1413083486View
Pancreatic cancer - Homo sapiens (human)72KEGG1392062386View
Calcium signaling pathway - Homo sapiens (human)177KEGG1384063416View
Ubiquitin mediated proteolysis - Homo sapiens (human)133KEGG1372373583View