BLCA  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples395
No. mutated genes17318
No. SNVs92371
No. CNAs4113

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP53194194660>>>>
TTN19119100>>>>
CDKN2A1602613138>>>>
ARID1A121977931>>>>
PIK3CA12086045>>>>
KDM6A1191028318>>>>
KMT2D114114810>>>>
MUC16113113240>>>>
RB1111696375>>>>
LRP1B10247165>>>>
ARNT999094>>>>
PPARG9813288>>>>
MCL1952094>>>>
CREBBP94482352>>>>
ERBB49011184>>>>
IKZF29013179>>>>
ING5894085>>>>
FAT185502542>>>>
SYNE17979160>>>>
ATM78531528>>>>
ERBB27748034>>>>
FGFR37554330>>>>
KMT2C7474330>>>>
RYR27474130>>>>
HMCN17373120>>>>
CCND1734069>>>>
PTPRD7227148>>>>
BPTF7028345>>>>
FLG707040>>>>
GATA3657259>>>>
CSMD16130235>>>>
EP3006161270>>>>
FAT46060160>>>>
BRIP15819347>>>>
CSMD3575790>>>>
DDX55610247>>>>
CLTC5517139>>>>
EIF4A25511344>>>>
STAG25555410>>>>
CCNE1543052>>>>
FHIT544050>>>>
TFRC549147>>>>
LPP5410044>>>>
DNAH5535350>>>>
AHNAK2535330>>>>
DNAH11535360>>>>
MACF1525240>>>>
TERT524049>>>>
OBSCN515160>>>>
CUBN515180>>>>
NF25110341>>>>
ASPSCR1505246>>>>
CD79B502049>>>>
XIRP2505070>>>>
MUC17505060>>>>
PRKAR1A493046>>>>
BIRC6494940>>>>
MDM2496145>>>>
NEB484880>>>>
ZFHX4484830>>>>
TUBD1486143>>>>
SYNE2484860>>>>
SOX2487143>>>>
RYR1484840>>>>
BDH1470047>>>>
PTEN4714835>>>>
RFNG471046>>>>
EWSR1476041>>>>
SRSF2465141>>>>
ETV5464143>>>>
ELF34646230>>>>
BCL6451044>>>>
CANT1451044>>>>
HRAS4516129>>>>
CBX8452143>>>>
TERC440044>>>>
SPTAN14444260>>>>
KMT2A4444230>>>>
ZNRF3444040>>>>
AHNAK434340>>>>
BCL2L1434240>>>>
PCLO434350>>>>
PDE4DIP4343110>>>>
RYR3434350>>>>
AKAP9424240>>>>
GPR98424250>>>>
EGFR427035>>>>
PHRF14113030>>>>
SPTA1414120>>>>
ERBB3414100>>>>
DNAH3414170>>>>
ANK2414140>>>>
TCHH404030>>>>
ROS14020122>>>>
FAT3393930>>>>
ARHGEF123913226>>>>
FREM2393970>>>>
LRP2393960>>>>
LINC00290380038>>>>
SACS383820>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG3912582489938View
Cell cycle - Homo sapiens (human)125KEGG3841138369483View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG383795226493View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG3801452148183View
Bladder cancer - Homo sapiens (human)42KEGG379634201455View
Focal adhesion - Homo sapiens (human)199KEGG3781751188272View
Prostate cancer - Homo sapiens (human)89KEGG378999280471View
Melanoma - Homo sapiens (human)71KEGG376751221471View
Glioma - Homo sapiens (human)65KEGG375754220471View
Non-small cell lung cancer - Homo sapiens (human)54KEGG373728175475View
MAPK signaling pathway - Homo sapiens (human)269KEGG3721590244110View
Pancreatic cancer - Homo sapiens (human)72KEGG371783199436View
Endocytosis - Homo sapiens (human)185KEGG3631105140337View
Calcium signaling pathway - Homo sapiens (human)177KEGG3581282136153View
p53 signaling pathway - Homo sapiens (human)68KEGG358586166384View
Small cell lung cancer - Homo sapiens (human)86KEGG356966222391View
Endometrial cancer - Homo sapiens (human)52KEGG351668119247View
Huntington's disease - Homo sapiens (human)179KEGG348964187230View
Wnt signaling pathway - Homo sapiens (human)150KEGG3451027210121View
Jak-STAT signaling pathway - Homo sapiens (human)155KEGG344742127234View