ACC  Firebrowse (January 28, 2016)


Dataset at a glance

No. Samples62
No. mutated genes9972
No. SNVs9568
No. CNAs252

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
ZFPM1242470>>>>
MUC5B222200>>>>
SOWAHA191900>>>>
LACTB191910>>>>
GARS191900>>>>
OBSCN181810>>>>
CCDC102A171700>>>>
MUC16171710>>>>
LRIG1161600>>>>
ZNRF3163213>>>>
TERT150015>>>>
MUC2151500>>>>
LINC00290140014>>>>
ZNF517131300>>>>
PLEC131330>>>>
TOR3A121200>>>>
ZNF598121200>>>>
OPRD1121200>>>>
TPO121200>>>>
TP53121270>>>>
NSD1113110>>>>
TTN111100>>>>
ZAR1111100>>>>
MAL21111110>>>>
PNMA6A100010>>>>
CRIPAK101000>>>>
CLDN23101000>>>>
AMDHD1101000>>>>
ATXN1101000>>>>
PRELID1100010>>>>
TRIOBP101010>>>>
ERCC2101000>>>>
KNDC19900>>>>
C1orf1069900>>>>
KCNK179900>>>>
PKHD19910>>>>
KBTBD139900>>>>
DSPP9930>>>>
TERF28008>>>>
SYT88800>>>>
GPRIN28800>>>>
IDUA8800>>>>
RGS9BP8800>>>>
RINL8800>>>>
TSC22D28810>>>>
SEMA5B8800>>>>
SEZ6L28800>>>>
CTNNB18810>>>>
ASPDH8800>>>>
CDKN2A8107>>>>
AHNAK28800>>>>
LETM18107>>>>
AKAP87215>>>>
FLG7710>>>>
APOE7700>>>>
NOTCH37306>>>>
WHSC17106>>>>
HMCN17700>>>>
FAT47730>>>>
PRKAR1A7601>>>>
C19orf107700>>>>
NF17770>>>>
ZNF6287700>>>>
BRD46115>>>>
C10orf956600>>>>
CDK126006>>>>
GPR986610>>>>
ERBB26006>>>>
FRAS16610>>>>
LRP116600>>>>
VARS6610>>>>
FAT16610>>>>
FGFR36006>>>>
HLA-B6640>>>>
GLTPD26600>>>>
RFNG6006>>>>
HHIPL16600>>>>
KMT2C6630>>>>
CCDC1056600>>>>
PLXNB36610>>>>
DST6600>>>>
PCDH156600>>>>
DIDO16620>>>>
LAMA26610>>>>
AATK6600>>>>
NEFH6600>>>>
MN16600>>>>
LASP16115>>>>
RGMB6600>>>>
RARA6115>>>>
BTBD116600>>>>
HRNR6610>>>>
LZTR16660>>>>
RASIP16600>>>>
SYNE16620>>>>
RYR26610>>>>
NOM16600>>>>
MYT1L5500>>>>
CDK45005>>>>
NMU5500>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG511863234View
Focal adhesion - Homo sapiens (human)199KEGG46164216View
Olfactory transduction - Homo sapiens (human)389KEGG46172130View
Cell adhesion molecules (CAMs) - Homo sapiens (human)133KEGG439290View
Neuroactive ligand-receptor interaction - Homo sapiens (human)256KEGG42139110View
MAPK signaling pathway - Homo sapiens (human)269KEGG41140306View
Calcium signaling pathway - Homo sapiens (human)177KEGG39135156View
ECM-receptor interaction - Homo sapiens (human)84KEGG3893100View
Tight junction - Homo sapiens (human)132KEGG388296View
Huntington's disease - Homo sapiens (human)179KEGG3773160View
Endocytosis - Homo sapiens (human)185KEGG3690146View
Alzheimer's disease - Homo sapiens (human)166KEGG368660View
Dilated cardiomyopathy - Homo sapiens (human)90KEGG3584115View
Aminoacyl-tRNA biosynthesis - Homo sapiens (human)41KEGG344330View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG34101166View
Bladder cancer - Homo sapiens (human)42KEGG3424929View
Purine metabolism - Homo sapiens (human)154KEGG336350View
Vascular smooth muscle contraction - Homo sapiens (human)115KEGG3379150View
Leukocyte transendothelial migration - Homo sapiens (human)116KEGG336981View
Pancreatic cancer - Homo sapiens (human)72KEGG3331823View