OV  TCGA Pan-Cancer


Dataset at a glance

No. Samples316
No. mutated genes11467
No. SNVs14527
No. CNAs3319

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP532962961030>>>>
MYC10300103>>>>
PARP10853083>>>>
CYC1831183>>>>
TERC750075>>>>
MECOM742072>>>>
LINC00536710071>>>>
CCNE1660066>>>>
BDH1561056>>>>
SOX2560056>>>>
TTN555500>>>>
USP35491148>>>>
INTS4470047>>>>
BRD4421041>>>>
NOTCH3413039>>>>
SAMD4B370037>>>>
PAF1360036>>>>
KRAS352033>>>>
GOLPH3L331032>>>>
MCL1320032>>>>
MYCL1310031>>>>
MRPL4291128>>>>
TERT291028>>>>
E2F3280028>>>>
NEDD9270027>>>>
RNF144B270027>>>>
SYNM273024>>>>
PRIC285260026>>>>
PTPRN2252023>>>>
BRAF252123>>>>
CCND1250025>>>>
G6PD243021>>>>
WHSC1242122>>>>
FGFR3241023>>>>
IGF1R241023>>>>
KDM5A241023>>>>
C1orf31230023>>>>
KAT6A233020>>>>
SOX17230023>>>>
LARP4B222020>>>>
AKT1220022>>>>
PDE11A224018>>>>
CBX8221021>>>>
LETM1220022>>>>
EZH2210021>>>>
PLB1216015>>>>
DLG5213018>>>>
KAT6B215116>>>>
KIAA1549201020>>>>
FAT1201109>>>>
USH2A202030>>>>
MLL3190019>>>>
TFE3190019>>>>
CSMD3191910>>>>
WAS191018>>>>
DPP6190019>>>>
MLLT4182116>>>>
FAT3181810>>>>
ZNF217181017>>>>
MTCP1181017>>>>
KCTD1181017>>>>
CREB3L2180018>>>>
GATA1180018>>>>
TCF3180018>>>>
ASCC2180018>>>>
NFE2L2180018>>>>
IKBKB181017>>>>
COX18170017>>>>
TAF4B170017>>>>
PIK3R1171116>>>>
MUC16171730>>>>
VDAC2171016>>>>
APC167111>>>>
INSR166010>>>>
LRP1B161303>>>>
NF1161284>>>>
AKR1C2160016>>>>
STK11160016>>>>
SMYD3160016>>>>
MRPS28150015>>>>
BCL2L1150015>>>>
FGFR1OP150015>>>>
RB115659>>>>
GALR1141013>>>>
BRCA1141094>>>>
EZR140014>>>>
HMCN1141420>>>>
LRP2141410>>>>
KDM2A144010>>>>
CSMD114727>>>>
PAX8141114>>>>
PDE4D140014>>>>
RYR2141400>>>>
PTEN132111>>>>
WHSC1L1131012>>>>
MRPS18A130013>>>>
BCL11A131012>>>>
LETM2130013>>>>
AHNAK121200>>>>
PARK2120012>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG314642166591View
MAPK signaling pathway - Homo sapiens (human)269KEGG311511132322View
Prostate cancer - Homo sapiens (human)89KEGG311382120328View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG311361115405View
Bladder cancer - Homo sapiens (human)42KEGG309333111276View
Colorectal cancer - Homo sapiens (human)84KEGG308369116275View
Pancreatic cancer - Homo sapiens (human)72KEGG307357122211View
Endometrial cancer - Homo sapiens (human)52KEGG307352113265View
Glioma - Homo sapiens (human)65KEGG307361114223View
Melanoma - Homo sapiens (human)71KEGG307351115228View
Cell cycle - Homo sapiens (human)125KEGG306398124267View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG306394115121View
Small cell lung cancer - Homo sapiens (human)86KEGG306409124322View
Non-small cell lung cancer - Homo sapiens (human)54KEGG306349114182View
Wnt signaling pathway - Homo sapiens (human)150KEGG305424119186View
Thyroid cancer - Homo sapiens (human)29KEGG305320108213View
Huntington's disease - Homo sapiens (human)179KEGG304416118145View
p53 signaling pathway - Homo sapiens (human)68KEGG302334106128View
Basal cell carcinoma - Homo sapiens (human)55KEGG30135511019View
Apoptosis - Homo sapiens (human)87KEGG29934910772View