LUSC  TCGA Pan-Cancer


Dataset at a glance

No. Samples178
No. mutated genes15246
No. SNVs48205
No. CNAs923

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP53141141440>>>>
TTN12512500>>>>
CSMD38181210>>>>
MUC167777100>>>>
RYR27676110>>>>
LRP1B696970>>>>
USH2A6767100>>>>
ZFHX4656560>>>>
SOX2641063>>>>
TERC570057>>>>
SYNE1525290>>>>
BDH1474043>>>>
RYR3414150>>>>
SPTA1404040>>>>
DNAH11393930>>>>
CDKN2A38261212>>>>
FAM135B373740>>>>
PKHD1373750>>>>
KMT2D3636190>>>>
SI363650>>>>
FLG363640>>>>
PKHD1L1363620>>>>
COL11A1353590>>>>
C1orf173343430>>>>
XIRP2333340>>>>
ZNF536333330>>>>
NAV3333360>>>>
CSMD1333241>>>>
WHSC1L13313226>>>>
LRP2333350>>>>
NFE2L2332707>>>>
CUBN323220>>>>
DMD313160>>>>
GPR98313120>>>>
HCN1313150>>>>
PAPPA2313130>>>>
MUC5B313140>>>>
MUC17313130>>>>
DNAH5313180>>>>
DNAH8313160>>>>
CDH10313160>>>>
COL22A1303070>>>>
KMT2C303080>>>>
CSMD2303040>>>>
PCLO303000>>>>
ZNF804B303040>>>>
CNTNAP5282830>>>>
APOB282840>>>>
NEB282840>>>>
LRRC7282830>>>>
DNAH9282840>>>>
ADAMTS12282850>>>>
MYH2282830>>>>
RP1282840>>>>
PIK3CA272700>>>>
ABCA13272740>>>>
BRINP3272700>>>>
SPHKAP272710>>>>
PCDH11X272720>>>>
DNAH7272740>>>>
ANK2272710>>>>
SLITRK3262600>>>>
MROH2B262680>>>>
FAT4262620>>>>
LETM2262126>>>>
RYR1262640>>>>
PXDNL252500>>>>
FAT3252510>>>>
FMN2252510>>>>
SCN1A252530>>>>
AHNAK2252520>>>>
CPS1252520>>>>
TPTE242450>>>>
HERC2242410>>>>
CNTNAP2242430>>>>
PCDH15242460>>>>
TNR242420>>>>
CDH18242420>>>>
ZNF208242410>>>>
PDE4DIP242430>>>>
CTNNA2242420>>>>
AHNAK232310>>>>
FAT12321112>>>>
BIRC6232310>>>>
LRRK2232320>>>>
CDH12232350>>>>
CRB1232330>>>>
MDN1232350>>>>
ANO1237021>>>>
PEG3232330>>>>
NRXN1222230>>>>
LAMA2222260>>>>
FBN2222240>>>>
BAI3222290>>>>
CCND1221021>>>>
KEAP1222220>>>>
BCL11A227017>>>>
DNAH10222240>>>>
VPS13B212120>>>>
LRFN5212120>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
MAPK signaling pathway - Homo sapiens (human)269KEGG17582213542View
Focal adhesion - Homo sapiens (human)199KEGG17597912063View
Olfactory transduction - Homo sapiens (human)389KEGG17515851160View
Pathways in cancer - Homo sapiens (human)329KEGG1751153186143View
Cell cycle - Homo sapiens (human)125KEGG17246010275View
Calcium signaling pathway - Homo sapiens (human)177KEGG1717979426View
Wnt signaling pathway - Homo sapiens (human)150KEGG1714798336View
Colorectal cancer - Homo sapiens (human)84KEGG1713747059View
Small cell lung cancer - Homo sapiens (human)86KEGG17151910867View
Prostate cancer - Homo sapiens (human)89KEGG1704158382View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG1703728881View
Neuroactive ligand-receptor interaction - Homo sapiens (human)256KEGG169905970View
Huntington's disease - Homo sapiens (human)179KEGG1694447616View
Glioma - Homo sapiens (human)65KEGG1693959183View
p53 signaling pathway - Homo sapiens (human)68KEGG1683048061View
Apoptosis - Homo sapiens (human)87KEGG1683176818View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG1684297711View
Melanoma - Homo sapiens (human)71KEGG1683618783View
Pancreatic cancer - Homo sapiens (human)72KEGG1673609080View
Endometrial cancer - Homo sapiens (human)52KEGG1673517150View