LUAD  TCGA Pan-Cancer


Dataset at a glance

No. Samples230
No. mutated genes16301
No. SNVs70580
No. CNAs345

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP53120120480>>>>
TTN11511500>>>>
MUC16105105220>>>>
CSMD39898210>>>>
RYR29292190>>>>
LRP1B8787220>>>>
ZFHX47777150>>>>
USH2A7373140>>>>
XIRP2676790>>>>
SPTA16666150>>>>
KRAS636005>>>>
FLG6161110>>>>
PCLO5757100>>>>
FAT3545480>>>>
NAV3525250>>>>
MUC17515170>>>>
APOB505050>>>>
COL11A15050160>>>>
CSMD1505090>>>>
GPR112474740>>>>
SI464680>>>>
FAT4444440>>>>
KMT2C444480>>>>
ANK2444470>>>>
ZNF536434380>>>>
ADAMTS12434370>>>>
RYR1434350>>>>
FAM135B424250>>>>
CDH10424280>>>>
HMCN1414190>>>>
RP1L1414150>>>>
CACNA1E414150>>>>
PTPRD404080>>>>
FBN2404090>>>>
KEAP1404040>>>>
ZNF804A393960>>>>
AHNAK2393920>>>>
PKHD1L1393950>>>>
SYNE1393940>>>>
RYR3393930>>>>
PAPPA2383860>>>>
DNAH9383890>>>>
PXDNL373750>>>>
FLG2373740>>>>
ZNF831363630>>>>
ABCA13363670>>>>
RELN363670>>>>
PCDH15363660>>>>
ASPM363620>>>>
NRXN1353550>>>>
TSHZ3353560>>>>
C1orf173353560>>>>
PCDH11X353500>>>>
NPAP1343420>>>>
TEX15343480>>>>
NLRP3343430>>>>
MAGEC1343430>>>>
MYH2343440>>>>
DNAH11343440>>>>
CSMD2333330>>>>
DMD333360>>>>
NALCN333350>>>>
BRINP3333340>>>>
MXRA5333350>>>>
TNR333360>>>>
RIMS2333350>>>>
MYH1333370>>>>
HRNR333390>>>>
OBSCN323230>>>>
CNTNAP5323220>>>>
FAT1323290>>>>
PTPRZ1313160>>>>
ASTN1313160>>>>
SVEP1313190>>>>
ADAMTS20313130>>>>
BAI3313150>>>>
CNTNAP2313160>>>>
COL6A3313140>>>>
TG313130>>>>
SORCS1313160>>>>
PKHD1313160>>>>
FRAS1313160>>>>
PEG3313140>>>>
SETBP1303050>>>>
LAMA2303030>>>>
EPHA6303030>>>>
DST303080>>>>
LRP2303020>>>>
PLXNA4303050>>>>
CPS1303060>>>>
PRDM9292980>>>>
PTPRB292930>>>>
FMN2292910>>>>
LPHN3292950>>>>
DCDC1292910>>>>
THSD7A292940>>>>
DNAH8292950>>>>
LYST292930>>>>
ADAMTS16292940>>>>
EGFR292705>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG222163228581View
MAPK signaling pathway - Homo sapiens (human)269KEGG215112118525View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG21497713312View
Focal adhesion - Homo sapiens (human)199KEGG210139322621View
Prostate cancer - Homo sapiens (human)89KEGG20853510145View
Calcium signaling pathway - Homo sapiens (human)177KEGG20711551398View
Olfactory transduction - Homo sapiens (human)389KEGG20722222100View
Colorectal cancer - Homo sapiens (human)84KEGG20453810325View
Pancreatic cancer - Homo sapiens (human)72KEGG20347410041View
Neuroactive ligand-receptor interaction - Homo sapiens (human)256KEGG20112551370View
Endometrial cancer - Homo sapiens (human)52KEGG2014478527View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG1994349853View
Cell cycle - Homo sapiens (human)125KEGG19849711344View
Glioma - Homo sapiens (human)65KEGG1984898944View
Melanoma - Homo sapiens (human)71KEGG1964699046View
Bladder cancer - Homo sapiens (human)42KEGG1963627351View
Small cell lung cancer - Homo sapiens (human)86KEGG19659713639View
Non-small cell lung cancer - Homo sapiens (human)54KEGG1964388033View
Wnt signaling pathway - Homo sapiens (human)150KEGG19359612115View
Tight junction - Homo sapiens (human)132KEGG1927028616View