LAML  TCGA Pan-Cancer


Dataset at a glance

No. Samples196
No. mutated genes6662
No. SNVs1822
No. CNAs0

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
NPM15454530>>>>
FLT3525260>>>>
DNMT3A5050130>>>>
IDH2202000>>>>
IDH1191900>>>>
RUNX11818100>>>>
TET21717170>>>>
NRAS151500>>>>
TP53141470>>>>
CEBPA131390>>>>
WT11212100>>>>
PTPN119900>>>>
KIT8810>>>>
U2AF18800>>>>
KRAS8800>>>>
SMC37720>>>>
SMC1A7710>>>>
TTN6600>>>>
PHF66640>>>>
STAG26660>>>>
BRINP35500>>>>
ASXL15550>>>>
RAD215550>>>>
PLCE14400>>>>
MUC163300>>>>
SMG13300>>>>
CACNA1E3300>>>>
PHACTR13320>>>>
SPEN3310>>>>
DNAH93300>>>>
CSMD13310>>>>
KDM6A3310>>>>
EZH23320>>>>
CROCC3300>>>>
CACNA1B3300>>>>
GBP43300>>>>
COL12A13300>>>>
SUZ123310>>>>
FCGBP3300>>>>
PTPRT3300>>>>
DIS33300>>>>
OR13H12200>>>>
MTUS22200>>>>
GATA22200>>>>
R3HCC1L2200>>>>
ILDR12200>>>>
STRN2200>>>>
DDX412210>>>>
GPR1122200>>>>
SETBP12200>>>>
PKHD1L12200>>>>
APOB2200>>>>
EPPK12200>>>>
GRM82200>>>>
OR11H122200>>>>
KIF2B2200>>>>
NRXN32200>>>>
KCNK132210>>>>
PPP1R3A2200>>>>
CBL2210>>>>
GIGYF22220>>>>
BSN2200>>>>
FAM57B2210>>>>
GRID12210>>>>
ABTB12220>>>>
SCAF82200>>>>
EGFR2200>>>>
GJB32210>>>>
RBBP42200>>>>
NMUR22200>>>>
E2F82210>>>>
SCN1A2200>>>>
FRYL2210>>>>
PRPF82200>>>>
TRPM32200>>>>
TUBA3C2200>>>>
PLEKHH12200>>>>
CBFB2220>>>>
MTMR82200>>>>
CRISPLD12200>>>>
CNTN52200>>>>
ZC3H182210>>>>
KDM3B2210>>>>
CD742200>>>>
CSMD32200>>>>
CADM22200>>>>
PHIP2210>>>>
FAM65A2200>>>>
GRIK42200>>>>
MTA22200>>>>
KIAA16832210>>>>
C17orf972200>>>>
BMPER2200>>>>
P2RY22200>>>>
TET12200>>>>
MED122210>>>>
ATP10B2200>>>>
CADPS2200>>>>
PRAMEF22200>>>>
CUL12200>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG126158380View
Acute myeloid leukemia - Homo sapiens (human)57KEGG108119270View
Cytokine-cytokine receptor interaction - Homo sapiens (human)262KEGG747770View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG6574190View
Hematopoietic cell lineage - Homo sapiens (human)87KEGG646570View
MAPK signaling pathway - Homo sapiens (human)269KEGG5769100View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG535880View
Cysteine and methionine metabolism - Homo sapiens (human)34KEGG5253130View
Cell cycle - Homo sapiens (human)125KEGG4549210View
Glutathione metabolism - Homo sapiens (human)50KEGG424400View
Glioma - Homo sapiens (human)65KEGG414780View
Endometrial cancer - Homo sapiens (human)52KEGG404470View
Prostate cancer - Homo sapiens (human)89KEGG404570View
Citrate cycle (TCA cycle) - Homo sapiens (human)31KEGG394000View
Melanoma - Homo sapiens (human)71KEGG394470View
Bladder cancer - Homo sapiens (human)42KEGG394270View
Non-small cell lung cancer - Homo sapiens (human)54KEGG394370View
Chemokine signaling pathway - Homo sapiens (human)190KEGG384330View
Tight junction - Homo sapiens (human)132KEGG384520View
Gap junction - Homo sapiens (human)90KEGG384000View