KIRC  TCGA Pan-Cancer


Dataset at a glance

No. Samples417
No. mutated genes12971
No. SNVs21039
No. CNAs72

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
VHL2142141200>>>>
PBRM11311301061>>>>
MUC4888800>>>>
TTN646400>>>>
SETD24848320>>>>
BAP13838250>>>>
MUC16333300>>>>
KDM5C2727170>>>>
MTOR252500>>>>
HMCN1191940>>>>
PABPC1191950>>>>
PTEN1818130>>>>
USH2A171760>>>>
KMT2C161690>>>>
AHNAK2161640>>>>
PCLO151520>>>>
GPR98151530>>>>
PIK3CA151214>>>>
SYNE1151520>>>>
KMT2D141420>>>>
DST141410>>>>
SPEN131330>>>>
FMN2131300>>>>
DNAH9131320>>>>
MAGEC1131310>>>>
MUC2131330>>>>
ATM121260>>>>
CSMD3121220>>>>
NEB121210>>>>
LRP1B121210>>>>
FAT3121210>>>>
ANKRD36121220>>>>
FBN2121240>>>>
ABCA13121210>>>>
LRP2121220>>>>
CSMD1121230>>>>
COL6A6121250>>>>
MUC17121230>>>>
NEFH121200>>>>
PKHD1L1121220>>>>
ARID1A121270>>>>
AKAP9111120>>>>
DNAH2111110>>>>
FLG111110>>>>
LYST111140>>>>
MUC6111120>>>>
PRRC2C111110>>>>
ZNFX1101010>>>>
NSD110416>>>>
SPTA1101010>>>>
NOTCH2101040>>>>
SMARCA4101010>>>>
XIRP2101020>>>>
BIRC6101010>>>>
COL5A3101040>>>>
MED13101010>>>>
PCDH15101000>>>>
DNAH7101020>>>>
DNAH8101020>>>>
ZNF717101070>>>>
PABPC3101020>>>>
DNAH10101020>>>>
RYR1101010>>>>
RYR3101010>>>>
RYR2101000>>>>
VPS13B9910>>>>
IGHV5-519900>>>>
HLA-DRB19910>>>>
SVEP19910>>>>
COL11A19940>>>>
CUL99900>>>>
WDFY39920>>>>
PRUNE29920>>>>
BAZ2B9910>>>>
RALGAPA19950>>>>
KCNJ129900>>>>
CNOT19930>>>>
HERC29900>>>>
LRP19920>>>>
MACF19900>>>>
SVIL9900>>>>
COL6A39900>>>>
FREM29900>>>>
THSD7B9920>>>>
MED12L9920>>>>
DNAH39920>>>>
DNAH59910>>>>
PKHD19910>>>>
TP539920>>>>
ANK29920>>>>
ANK39920>>>>
DHX379920>>>>
GREB19900>>>>
DNHD19900>>>>
SYNE29940>>>>
MYO3A8800>>>>
SDK18830>>>>
CHD78800>>>>
AHNAK8810>>>>
GPRIN18800>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG35873920512View
Ubiquitin mediated proteolysis - Homo sapiens (human)133KEGG2843981550View
Renal cell carcinoma - Homo sapiens (human)70KEGG2573081308View
Focal adhesion - Homo sapiens (human)199KEGG254427859View
MAPK signaling pathway - Homo sapiens (human)269KEGG234337623View
Calcium signaling pathway - Homo sapiens (human)177KEGG220301451View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG207297477View
Olfactory transduction - Homo sapiens (human)389KEGG198296480View
Neuroactive ligand-receptor interaction - Homo sapiens (human)256KEGG189257350View
Endocytosis - Homo sapiens (human)185KEGG183248503View
ECM-receptor interaction - Homo sapiens (human)84KEGG178230550View
Dilated cardiomyopathy - Homo sapiens (human)90KEGG163208280View
Tight junction - Homo sapiens (human)132KEGG156198610View
Insulin signaling pathway - Homo sapiens (human)137KEGG155198196View
Chemokine signaling pathway - Homo sapiens (human)190KEGG154190256View
Cytokine-cytokine receptor interaction - Homo sapiens (human)262KEGG153183203View
Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)83KEGG150185230View
Axon guidance - Homo sapiens (human)129KEGG148181352View
PBAF.2; PBAF(Tjian); SWI/SNF13PINdb1471541101View
PBAF; SWI/SNF; hSWI/SNF-B; SWI/SNF-B; BRG112PINdb1461521101View