HNSC  TCGA Pan-Cancer


Dataset at a glance

No. Samples306
No. mutated genes15176
No. SNVs42715
No. CNAs1121

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TP53213213900>>>>
TTN13713700>>>>
PIK3CA8664028>>>>
CDKN2A85645021>>>>
PPFIA1855184>>>>
CCND1791078>>>>
FAT17272600>>>>
CSMD37070140>>>>
MUC166868100>>>>
LRP1B626270>>>>
NOTCH15959250>>>>
KMT2D5656370>>>>
SYNE1555580>>>>
FLG484870>>>>
PCLO434340>>>>
DNAH5424290>>>>
USH2A404070>>>>
FRG1B373750>>>>
SI353580>>>>
PKHD1L1343460>>>>
RYR2343440>>>>
NSD13333220>>>>
SOX2333030>>>>
RELN313140>>>>
FAM135B313110>>>>
EGFR3114122>>>>
NFE2L23117014>>>>
LAMA2303030>>>>
DMD303050>>>>
GPR98292940>>>>
TLN12812017>>>>
COL11A1282880>>>>
MUC17282820>>>>
DNAH7282820>>>>
PLEC282850>>>>
CUBN272730>>>>
CSMD1272622>>>>
CASP82727130>>>>
APOB262640>>>>
NEB262620>>>>
XIRP2262610>>>>
PAPPA2262630>>>>
TERC260026>>>>
DNAH11262620>>>>
FAT4252500>>>>
EP300252550>>>>
PCDH15252550>>>>
DNAH9252550>>>>
RYR3252520>>>>
BDH1241023>>>>
ZFHX4242430>>>>
FAT3242430>>>>
LRP2242410>>>>
RP1242430>>>>
CTNND2232340>>>>
KMT2C232370>>>>
ASPM232320>>>>
HUWE1232330>>>>
CDH10232310>>>>
PEG3232330>>>>
AHNAK222230>>>>
NAV3222220>>>>
FMN2222200>>>>
MUC5B222210>>>>
KALRN222220>>>>
DCHS2222270>>>>
SYNE2222220>>>>
LETM2223119>>>>
VPS13B212150>>>>
ASXL3212140>>>>
NPAP1212100>>>>
COL22A1212150>>>>
MACF1212130>>>>
PCDH11X212110>>>>
UNC13C212160>>>>
ZNF804B212120>>>>
AKAP9202060>>>>
FAT2202070>>>>
ABCA13202030>>>>
WHSC1L1201019>>>>
SCN1A202010>>>>
DST202070>>>>
THSD7A202040>>>>
DNAH8202040>>>>
ANK2202020>>>>
PRDM9202010>>>>
FGFR1191018>>>>
ZNF99191900>>>>
PTPRT191940>>>>
SEMA5A191940>>>>
HERC2191940>>>>
NBPF10191910>>>>
ZNF208191930>>>>
AHNAK2191930>>>>
TENM1191920>>>>
KDM2A181017>>>>
NRXN1181820>>>>
LRRC4C181810>>>>
SVEP1181820>>>>
SPTA1181830>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG3001349287251View
Prostate cancer - Homo sapiens (human)89KEGG287555129197View
MAPK signaling pathway - Homo sapiens (human)269KEGG28687718066View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG286533171189View
Small cell lung cancer - Homo sapiens (human)86KEGG283603137154View
Pancreatic cancer - Homo sapiens (human)72KEGG282557184197View
Focal adhesion - Homo sapiens (human)199KEGG281922111171View
Wnt signaling pathway - Homo sapiens (human)150KEGG28060813895View
Glioma - Homo sapiens (human)65KEGG280536165190View
Melanoma - Homo sapiens (human)71KEGG280526167209View
Non-small cell lung cancer - Homo sapiens (human)54KEGG280514162177View
Endometrial cancer - Homo sapiens (human)52KEGG279477114154View
Cell cycle - Homo sapiens (human)125KEGG278576189140View
Apoptosis - Homo sapiens (human)87KEGG27644811952View
Colorectal cancer - Homo sapiens (human)84KEGG275535131152View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG27255311942View
Huntington's disease - Homo sapiens (human)179KEGG26452814220View
Bladder cancer - Homo sapiens (human)42KEGG262393159155View
p53 signaling pathway - Homo sapiens (human)68KEGG261429173134View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG2616727776View