GBM  TCGA Pan-Cancer


Dataset at a glance

No. Samples291
No. mutated genes11382
No. SNVs15997
No. CNAs858

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
EGFR145771128>>>>
PTEN9088402>>>>
CDKN2A892288>>>>
TP538583173>>>>
TTN747400>>>>
MUC16474730>>>>
CDK4440044>>>>
PDGFRA4311040>>>>
FLG333330>>>>
PIK3R1323290>>>>
NF13131260>>>>
MDM4301029>>>>
RB12925235>>>>
RYR2292900>>>>
PIK3CA282820>>>>
PCLO272750>>>>
SPTA1272740>>>>
MDM2262124>>>>
MUC17232300>>>>
HMCN1191930>>>>
AHNAK2191910>>>>
LRP2181830>>>>
RYR3181840>>>>
FRG1B171730>>>>
ATRX1717110>>>>
OBSCN161620>>>>
USH2A161600>>>>
DNAH5161610>>>>
TCHH161600>>>>
PKHD1161610>>>>
KEL151530>>>>
IDH1151500>>>>
GPR98141410>>>>
COL6A3141430>>>>
CNTNAP2141400>>>>
NBPF10141400>>>>
FRAS1141410>>>>
SYNE1141410>>>>
APOB131320>>>>
TNFRSF9131012>>>>
KRTAP4-11131300>>>>
ERRFI1130013>>>>
MUC4131300>>>>
RELN131330>>>>
DNAH2131320>>>>
SDK1121200>>>>
MROH2B121220>>>>
HCN1121220>>>>
FGFR312428>>>>
COL1A2121200>>>>
DSP121210>>>>
FLG2121240>>>>
DNAH8121220>>>>
NLRP5121200>>>>
STAG21212100>>>>
DMD111100>>>>
ZNF814111100>>>>
FBN3111100>>>>
POTEC111100>>>>
HRNR111110>>>>
DOCK5111100>>>>
SEMA3C111110>>>>
GABRA6111100>>>>
SCN9A111100>>>>
CDKN2C11338>>>>
FCGBP111110>>>>
DNAH3111100>>>>
CCND211219>>>>
CDH18111110>>>>
FAT2111110>>>>
RIMS2111130>>>>
CHD9101000>>>>
CHD8101070>>>>
SPAG17101000>>>>
KMT2C101000>>>>
PRDM9101010>>>>
SLIT3101000>>>>
CD3310406>>>>
RPL2210119>>>>
ABCB1101010>>>>
LZTR1101000>>>>
ABCC9101010>>>>
DNAH11101000>>>>
GRIN2A9900>>>>
SEMG19910>>>>
AHNAK9910>>>>
F59930>>>>
DSG39900>>>>
PIK3C2G9910>>>>
RPSAP589900>>>>
MXRA59900>>>>
LRP19920>>>>
RBM479900>>>>
PCDH11X9900>>>>
THSD7B9900>>>>
ADAM299910>>>>
DNAH99900>>>>
KDR9930>>>>
DRD59900>>>>
LAMA19900>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG284705138378View
Glioma - Homo sapiens (human)65KEGG276421101349View
Melanoma - Homo sapiens (human)71KEGG276405100355View
Prostate cancer - Homo sapiens (human)89KEGG271438105219View
Non-small cell lung cancer - Homo sapiens (human)54KEGG26731160284View
Pancreatic cancer - Homo sapiens (human)72KEGG26631963280View
Focal adhesion - Homo sapiens (human)199KEGG26456489193View
MAPK signaling pathway - Homo sapiens (human)269KEGG26043874191View
Endometrial cancer - Homo sapiens (human)52KEGG25937074145View
Bladder cancer - Homo sapiens (human)42KEGG25522750312View
Colorectal cancer - Homo sapiens (human)84KEGG25232336185View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG25135533183View
Calcium signaling pathway - Homo sapiens (human)177KEGG24235725168View
Small cell lung cancer - Homo sapiens (human)86KEGG24238210375View
p53 signaling pathway - Homo sapiens (human)68KEGG23822467209View
Olfactory transduction - Homo sapiens (human)389KEGG236504370View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG23324360188View
Cytokine-cytokine receptor interaction - Homo sapiens (human)262KEGG22926924185View
Cell cycle - Homo sapiens (human)125KEGG22923879204View
Endocytosis - Homo sapiens (human)185KEGG22822718209View