COADREAD  TCGA Pan-Cancer


Dataset at a glance

No. Samples224
No. mutated genes16147
No. SNVs63169
No. CNAs545

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
APC1731731670>>>>
TP53120120370>>>>
KRAS979711>>>>
TTN818100>>>>
SYNE1494990>>>>
PIK3CA454500>>>>
FAT4404050>>>>
LRP1B393980>>>>
FBXW7383880>>>>
MUC16383850>>>>
LRP2373740>>>>
DNAH5343460>>>>
DMD333380>>>>
FLG323210>>>>
HMCN1313150>>>>
ANK2313150>>>>
RYR2303040>>>>
CSMD1292753>>>>
FAT2292930>>>>
ANK12918111>>>>
SMAD4292633>>>>
CSMD3282850>>>>
COL6A3282830>>>>
SDK1272710>>>>
ATM272592>>>>
USH2A272740>>>>
TCF7L2272790>>>>
PKHD1262650>>>>
DNAH2262630>>>>
HYDIN252550>>>>
ACVR2A2525220>>>>
AMER12525190>>>>
MDN1252550>>>>
CSMD2242420>>>>
CUBN242410>>>>
ZFHX4242430>>>>
FREM2242430>>>>
DCHS2242440>>>>
RYR1242400>>>>
TGFBR22323190>>>>
AHNAK2232330>>>>
ARID1A2321122>>>>
RYR3232330>>>>
PCDH9222210>>>>
ABCA12222220>>>>
SACS222250>>>>
BRAF222200>>>>
LIFR221844>>>>
TENM1222230>>>>
DNAH10222230>>>>
ZC3H132121140>>>>
TECTA212110>>>>
APOB212130>>>>
DOCK2212140>>>>
RELN212100>>>>
COL12A1212120>>>>
KAT6A2111010>>>>
NRXN1202020>>>>
CHD6201624>>>>
VPS13B202010>>>>
PTPRM202020>>>>
MYH11202020>>>>
NALCN202010>>>>
WDFY3202050>>>>
DLC1202020>>>>
PCDH15202040>>>>
NRAS202000>>>>
PDZD2202050>>>>
CREBBP191940>>>>
GRIN2A191910>>>>
NEB191950>>>>
FBN2191910>>>>
ATP10A191940>>>>
ABCA13191930>>>>
TMEM132D191910>>>>
LRRK2191930>>>>
DNAH8191950>>>>
PRDM2191930>>>>
PCLO191920>>>>
VCAN191940>>>>
AKAP9181870>>>>
FN1181820>>>>
OBSCN181840>>>>
MAP1B181830>>>>
EVC2181810>>>>
ROBO1181810>>>>
TRRAP181830>>>>
TENM3181840>>>>
BAI3181830>>>>
MACF1181800>>>>
CACNA1E181810>>>>
ERBB4181820>>>>
DNAH3181850>>>>
DNAH9181840>>>>
DYSF181830>>>>
LAMA1181820>>>>
ADAMTS12181810>>>>
KALRN181820>>>>
WBSCR17181820>>>>
ANK3181830>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG224180746492View
Colorectal cancer - Homo sapiens (human)84KEGG22188231022View
Endometrial cancer - Homo sapiens (human)52KEGG22170925130View
Wnt signaling pathway - Homo sapiens (human)150KEGG21984928730View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG21911002522View
MAPK signaling pathway - Homo sapiens (human)269KEGG216110216126View
Basal cell carcinoma - Homo sapiens (human)55KEGG2154972441View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG2135679844View
Prostate cancer - Homo sapiens (human)89KEGG2126399233View
Pancreatic cancer - Homo sapiens (human)72KEGG21157710440View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG2066668616View
Glioma - Homo sapiens (human)65KEGG2065187115View
Non-small cell lung cancer - Homo sapiens (human)54KEGG2064795915View
Thyroid cancer - Homo sapiens (human)29KEGG2053736118View
Melanoma - Homo sapiens (human)71KEGG2054847115View
Bladder cancer - Homo sapiens (human)42KEGG2053825225View
Small cell lung cancer - Homo sapiens (human)86KEGG20553810645View
Apoptosis - Homo sapiens (human)87KEGG1923987628View
Cell cycle - Homo sapiens (human)125KEGG19154711633View
Focal adhesion - Homo sapiens (human)199KEGG190111614430View