BLCA  TCGA Pan-Cancer


Dataset at a glance

No. Samples99
No. mutated genes12979
No. SNVs21657
No. CNAs439

Most Mutated Genes


Gene
Mutated
Samples

SNVs
Inactivating
SNVs

CNAs
View MutationsView Annotations
TTN545400>>>>
TP535050130>>>>
MUC16343450>>>>
ARID1A2727230>>>>
KMT2D2626180>>>>
KDM6A2424230>>>>
KMT2C242470>>>>
SYNE1212130>>>>
CDKAL1191018>>>>
FLG191930>>>>
E2F3192118>>>>
PIK3CA191801>>>>
EP300171760>>>>
HMCN1161630>>>>
RYR2161630>>>>
CSMD3151520>>>>
AHNAK2151510>>>>
RB11514122>>>>
SYNE2151510>>>>
LRP1B141400>>>>
ZFHX4141410>>>>
PDE4DIP141321>>>>
MUC17141400>>>>
PPARG142012>>>>
CDKN1A1313100>>>>
FRG1B131300>>>>
FLJ42969130013>>>>
KMT2A131360>>>>
FREM2131330>>>>
ERCC2131300>>>>
PKHD1L1131330>>>>
HRNR131310>>>>
GPR98121200>>>>
AHNAK121200>>>>
FAT1121270>>>>
FGFR312816>>>>
CDKN2A12438>>>>
FLG2121200>>>>
LAMA3121230>>>>
LYST121220>>>>
CREBBP121260>>>>
DNAH3121210>>>>
COL7A1111120>>>>
ATM111120>>>>
CSMD2111100>>>>
NOTCH211843>>>>
FAT4111150>>>>
BIRC6111120>>>>
UBR4111100>>>>
USH2A111110>>>>
DNAH5111110>>>>
DNAH11111110>>>>
MCL110308>>>>
ZNF91101000>>>>
ERBB3101000>>>>
ZNF845101010>>>>
NEB101000>>>>
LAMA2101020>>>>
FBXW7101050>>>>
WDFY3101010>>>>
SCN1A101000>>>>
ABCA13101040>>>>
ARNT10109>>>>
PCLO101020>>>>
HERC1101030>>>>
MACF1101010>>>>
TRIO101010>>>>
CELSR3101010>>>>
KIAA2018101010>>>>
STAG2101080>>>>
ANKRD30A101000>>>>
ANK2101020>>>>
SRCAP101020>>>>
VCAN101000>>>>
CHD79910>>>>
AKAP99910>>>>
ERBB29606>>>>
PCNT9900>>>>
NKTR9910>>>>
SPTA19900>>>>
XIRP29910>>>>
EIF4G39900>>>>
FAT39910>>>>
HCN19920>>>>
DEPDC59930>>>>
AFF39900>>>>
DMXL29900>>>>
LRRC79910>>>>
HECTD49930>>>>
GOLGB19920>>>>
LRP29920>>>>
LRP19910>>>>
RELN9910>>>>
ARHGAP329920>>>>
COL6A69900>>>>
NCOR19940>>>>
DSP9910>>>>
FRY9910>>>>
INO809910>>>>
DNAH19910>>>>

Mutations plot


Most Mutated Pathways

Gene SetNo. GenesDatabaseMutated Samples SNVsInactivating SNVsCNAsTop 5 Genes
Pathways in cancer - Homo sapiens (human)329KEGG97624118116View
Focal adhesion - Homo sapiens (human)199KEGG953994627View
MAPK signaling pathway - Homo sapiens (human)269KEGG943725829View
Regulation of actin cytoskeleton - Homo sapiens (human)213KEGG923203219View
Cell cycle - Homo sapiens (human)125KEGG902617858View
Endocytosis - Homo sapiens (human)185KEGG902743523View
Small cell lung cancer - Homo sapiens (human)86KEGG902415454View
Prostate cancer - Homo sapiens (human)89KEGG892416864View
Calcium signaling pathway - Homo sapiens (human)177KEGG883122423View
Olfactory transduction - Homo sapiens (human)389KEGG87320246View
Glioma - Homo sapiens (human)65KEGG861804661View
Bladder cancer - Homo sapiens (human)42KEGG851374172View
Pancreatic cancer - Homo sapiens (human)72KEGG841734263View
Melanoma - Homo sapiens (human)71KEGG841704755View
Chronic myeloid leukemia - Homo sapiens (human)75KEGG841905466View
Wnt signaling pathway - Homo sapiens (human)150KEGG832574517View
Jak-STAT signaling pathway - Homo sapiens (human)155KEGG831723221View
Colorectal cancer - Homo sapiens (human)84KEGG831833128View
Neurotrophin signaling pathway - Homo sapiens (human)126KEGG822093113View
Huntington's disease - Homo sapiens (human)179KEGG822254219View